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ProteomicsPhosphoproteome of glioblastoma cells after FG1059 treatment
We found that RPL22L1 isoform switch is regulated by SRSF4 protein and identified a small molecule compound FG1059, that inhibits this process and decreases tumor growth. To confirm that FG1059 affects RPL22L1 due to the inhibition of SRSF protein phosphorylation we studied the phosphoproteome of pa...
ORGANISM(S): Homo sapiens (Human) 
2023-10-24 | PXD035855 | Pride
Glioblastoma Ribosome Rna splicing Rpl22l1 Intratumoral heterogeneity 
ProteomicsLC-MS/MS identification of proteins that were bound to recombinant His-tagged isoforms of RPL22L1
Glioblastoma (GBM) is characterized by an exceptionally high intratumoral heterogeneity. However, the molecular mechanisms underlying the origin of different GBM cell populations remain unclear. Here we found that the composition of ribosomes of GBM cells in the tumor core and edge differ due to alt...
ORGANISM(S): Homo sapiens (Human) 
2023-10-24 | PXD035849 | Pride
Glioblastoma Ribosome Rna splicing Rpl22l1 Intratumoral heterogeneity 
ProteomicsLC-MS/MS identification of proteins that were co-purified with Fc-tagged isoforms of RPL22L1
Glioblastoma (GBM) is characterized by an exceptionally high intratumoral heterogeneity. However, the molecular mechanisms underlying the origin of different GBM cell populations remain unclear. Here we found that the composition of ribosomes of GBM cells in the tumor core and edge differ due to alt...
ORGANISM(S): Homo sapiens (Human) 
2023-10-24 | PXD035767 | Pride
Glioblastoma Ribosome Rna splicing Rpl22l1 Intratumoral heterogeneity 
ProteomicsThe pathogenesis of Guillain-Barre syndrome: peptidomic profiling of physiological fluids
Acute inflammatory demyelinating polyneuropathy (AIDP) - one of the forms of Guillain-Barre syndrome (GBS) - is a rare and severe disorder of the peripheral nervous system that also has an unknown etiology. One of the hallmarks of AIDP pathogenesis is a significantly elevated cerebrospinal fluid (CS...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2016-07-20 | MSV000079963 | MassIVE
ProteomicsThe pathogenesis of Guillain-Barre syndrome: immunological profiling of physiological fluids
Acute inflammatory demyelinating polyneuropathy (AIDP) - one of the forms of Guillain-Barre syndrome (GBS) - is a rare and severe disorder of the peripheral nervous system that also has an unknown etiology. One of the hallmarks of AIDP pathogenesis is a significantly elevated cerebrospinal fluid (CS...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2016-07-20 | MSV000079941 | MassIVE
ProteomicsProteome profiling of ovarian cancer and cirrhosis ascites
Proteome-metabolome profiling of ovarian cancer ascites reveals novel components involved in intercellular communication http://www.mcponline.org/content/early/2014/09/30/mcp.M114.041194.full.pdf+html?sid=78e7a955-fa54-4ded-b296-89f1fb6adbec
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2016-07-19 | MSV000079934 | MassIVE
ProteomicsProteome profiling of microvesicles, exosomes and supernatant from SKOV3
Proteome-metabolome profiling of ovarian cancer ascites reveals novel components involved in intercellular communication http://www.mcponline.org/content/early/2014/09/30/mcp.M114.041194.full.pdf+html?sid=78e7a955-fa54-4ded-b296-89f1fb6adbec
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2016-07-22 | MSV000079992 | MassIVE
OtherProteome-metabolome profiling of ovarian cancer ascites reveals novel components involved in intercellular communication.
Data from ProteomeXchange, PXD ID: PXD001403. File: V022-V023+V053_line8_MGFPeaklist.mgf. Published as part of Mol Cell Proteomics. 2014 Sep 30 . From the Abstract: {{i}} The aim of this study was to elucidate specific features of malignant ascites metabolome and proteome. To omit components that b...
ORGANISM(S): Homo_sapiens_viruses, Human 
GPM11210030783 | GPMDB
Resource Reanalysis 
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