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TranscriptomicsTranscription profiling of transgenic mice (tTA/IkappaBalpha-AA) treated with doxycycline (DOX), which represses expression of the transgenic IkappaBalpha
double transgenic mice (tTA/IkappaBalpha-AA) were treated with doxycycline (DOX), which represses expression of the transgenic IkappaBalpha. Double transgenic mice without Dox-treatment overexpress the transdominant IkappaBalpha, which represses NFkappaB activation.
ORGANISM(S): Mus musculus 
2006-05-10 | E-MEXP-358 | biostudies-arrayexpress
TranscriptomicsTranscriptional changes associated with miR-6762-5p expression in Hela cells
Decipher the direct and indirect targets of human miR-6762-5p by doxycyclin-inducible expression in HeLa cells
ORGANISM(S): Homo sapiens 
2024-12-01 | E-MTAB-14115 | biostudies-arrayexpress
TranscriptomicsTranscriptional changes associated with miR-6762-5p expression in HCT116 cells
Decipher the direct and indirect targets of human miR-6762-5p by doxycyclin-inducible expression in HCT116 cells
ORGANISM(S): Homo sapiens 
2024-12-01 | E-MTAB-14122 | biostudies-arrayexpress
TranscriptomicsmiRNA profiling of human colon cells infected with the bacterium Shigella flexneri
Overview of microRNA expression changes during Shigella flexneri infection of human colon epithelial cells (HCT116)
ORGANISM(S): Homo sapiens 
2024-12-01 | E-MTAB-14092 | biostudies-arrayexpress
TranscriptomicsDual-transcriptome of Shigella flexneri infecting human HCT116 cells
Analyse the transcriptionnal changes of human colon epithelial cells (HCT116) associated with Shigella flexneri (M90T) infection and correlated with the bacterial transcriptional program.
ORGANISM(S): Homo sapiens 
2024-12-01 | E-MTAB-14119 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human Caco-2 intestinal epithelial cell line infected with wild type Shigella flexneri and a OspF mutantt reveals an injected bacterial effector targets chromatin access for NF-kB as a strategy to shape transcription of immune genes
Phosphorylation of histone H3 at Serine 10 emerges as a mechanism increasing chromatin accessibility of the transcription factor NF-kB for a particular set of immune genes. Here we report that a bacterial pathogen uses this strategy to shape the transcriptional response of infected host cells. We id...
ORGANISM(S): Homo sapiens 
2008-06-14 | E-GEOD-6082 | biostudies-arrayexpress
TranscriptomicsImpact of HP1gamma and HP1gamma S83 phosphorylation on the transcriptionnal effect of PMA stimulation of mouse fibroblasts
We have here followed the transcriptional effect of stimulation with the phorbol ester PMA in mouse fibroblasts from HP1gamma null mice recomplemented with either wild-type HP1gamma or an HP1g with an S83A mutation Spontaneously immortalized mouse embryonic fibroblasts from HP1gamma null mice were u...
ORGANISM(S): Mus musculus 
2014-11-01 | E-GEOD-60283 | biostudies-arrayexpress
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