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TranscriptomicsLoss of Caenorhabditis elegans UNG-1 uracil-DNA glycosylase affects apoptosis in response to DNA damaging agents.
The nematode Caenorhabditis elegans has been used extensively to study responses to DNA damage. In contrast, little is known about DNA repair in this organism. C. elegans is unusual in that it encodes few DNA glycosylases and the uracil-DNA glycosylase (UDG) encoded by the ung-1 gene is the only kno...
ORGANISM(S): Caenorhabditis elegans 
2010-06-08 | E-GEOD-21467 | biostudies-arrayexpress
TranscriptomicsExpression changes in Caenorhabditis elegans xpa-1 mutant
Background: The ability of an organism to repair DNA damage is implicated in carcinogenesis and aging. Interestingly expression profiling of Nucleotide Excision Repair (NER) deficient segmental progeroid mice revealed gene expression changes resembling these observed in aged wild type animals. Our p...
ORGANISM(S): Caenorhabditis elegans 
2013-05-03 | E-GEOD-39252 | biostudies-arrayexpress
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