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ProteomicsArg-GlcNAc analysis of the proteins GlmR and NagC
This project explores the Arg-GlcNAcylation on Salmonella proteins GlmR and NagC. Using MS analysis and Site directed mutagenesis we show Arg-GlcNAcylation occurs on these salmonella enzymes.
ORGANISM(S): Salmonella enterica subsp. enterica serovar Typhimurium str. SL1344 
2022-03-10 | PXD030710 | Pride
Arg-glcnac 
Proteomicsidentification of the endogenous insoluble host targets of the Salmonella effectors SSeK3
Strains of Salmonella utilise two distinct type three secretion systems to deliver effector proteins directly into host cells. The Salmonella effector SseK3 is a arginine glycosyltransferase that modify mammalian proteins with N-acetyl glucosamine (GlcNAc). Here, we used Arg-GlcNAc glycopeptide immu...
ORGANISM(S): Mus musculus (Mouse) 
2020-07-28 | PXD015082 | Pride
Glycosylation Salmonella Proteomics Arg-glcnac Ssek3 
Proteomicsidentification of the endogenous host targets of the Salmonella effectors SSeK1 and 3
Strains of Salmonella utilise two distinct type three secretion systems to deliver effector proteins directly into host cells. The Salmonella effectors SseK1 and SseK3 are arginine glycosyltransferases that modify mammalian death domain containing proteins with N-acetyl glucosamine (GlcNAc) when ove...
ORGANISM(S): Homo sapiens (Human) Mus musculus (Mouse) Salmonella enterica subsp. enterica serovar Typhimurium str. SL1344 
2019-03-27 | PXD010769 | Pride
Glycosylation Salmonella Proteomics Infection Glycopeptide enrichment 
UnknownArginine glycosylation regulates UDP-GlcNAc biosynthesis in Salmonella enterica.
Not available
S-EPMC8964723 | biostudies-literature
UnknownNleB2 from enteropathogenic Escherichia coli is a novel arginine-glucose transferase effector.
Not available
S-EPMC8238200 | biostudies-literature
UnknownArginine GlcNAcylation of Rab small GTPases by the pathogen Salmonella Typhimurium.
Not available
S-EPMC7275070 | biostudies-literature
UnknownSalmonella Effectors SseK1 and SseK3 Target Death Domain Proteins in the TNF and TRAIL Signaling Pathways.
Not available
S-EPMC6553940 | biostudies-literature
UnknownArginine GlcNAcylation and Activity Regulation of PhoP by a Type III Secretion System Effector in Salmonella.
Not available
S-EPMC8811161 | biostudies-literature
UnknownSTD NMR Epitope Perturbation by Mutation Unveils the Mechanism of YM155 as an Arginine-Glycosyltransferases Inhibitor Effective in Treating Enteropathogenic Diseases.
Not available
S-EPMC11937963 | biostudies-literature
UnknownAtomic-resolution crystal structures of the immune protein conglutinin from cow reveal specific interactions of its binding site with <i>N</i>-acetylglucosamine.
Not available
S-EPMC6851296 | biostudies-literature
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