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Most available knowledge on fungal arginine metabolism is derived from studies on Saccharomyces cerevisiae, in which arginine catabolism is initiated by releasing urea via the arginase reaction. Orthologs of the S. cerevisiae genes encoding the first three enzymes in the arginase pathway were cloned...
ORGANISM(S): Kluyveromyces lactis 
Xanthomonas oryzae pv. oryzae (Xoo), the causative agent of bacterial blight disease, is one of the major threats to rice productivity. Yet, the molecular mechanism of rice-Xoo interaction is elusive. Here, we report comparative proteome profiles of Xoo susceptible (Dongjin) and resistant (Hwayeong)...
ORGANISM(S): Oryza sativa subsp. japonica (Rice) 
2022-01-06 | PXD027569 | Pride
Background: Pulmonary Fibrosis (PF) is an interstitial lung disease of unknown etiology, characterized by excessive accumulation of extracellular matrix in the lungs, which disrupts the structure and gas exchange of the alveoli. There are only two approved therapies for PF, nintedanib (Nib) and pirf...
ORGANISM(S): Mus musculus (Mouse) 
2021-09-10 | PXD024058 | Pride
We studied the differential gene expression in the gastric cell line AGS infected with wild type (WT) or arginase gene mutant (rocF) Helicobacter pylori (Hp). We found that the presence of the gene regulates the inflammatory responses in terms of IL8 and MIP-1B. We conclude that arginase may be invo...
ORGANISM(S): Homo sapiens 
Hepatic arginase deficiency fosters dysmyelination during postnatal CNS development
Arginine and polyamine availability modulates Toxoplasma growth independent of host arginase 2
Arginase inhibitor reduces fungal dissemination in murine pulmonary cryptococcosis by promoting anti-cryptococcal immunity
The effects of Arginase 2 (Arg2) knockout on chronic hypoxia-induced pulmonary hypertension
CD4 T cell intrinsic Arginase 1 controls the kinetics of Th1 induction and contraction
Toxoplasma gondii is an obligate intracellular parasite that relies on host cell metabolism for essential nutrients it cannot synthesize independently, including arginine and its downstream products, polyamines. Hosts express two arginine-degrading enzymes: arginase 1, which is essential for ammonia...
ORGANISM(S): Mus musculus 
2026-09-11 | GSE346445 | GEO
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