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ProteomicsTianlongkechuanling Inhibits Pulmonary Fibrosis Through Down-Regulation Of Arginase-Ornithine Pathway
Background: Pulmonary Fibrosis (PF) is an interstitial lung disease of unknown etiology, characterized by excessive accumulation of extracellular matrix in the lungs, which disrupts the structure and gas exchange of the alveoli. There are only two approved therapies for PF, nintedanib (Nib) and pirf...
ORGANISM(S): Mus musculus (Mouse) 
2021-09-10 | PXD024058 | Pride
Proteomics Pulmonary fibrosis Arginase-ornithine pathway Arginase Tianlongkechuanling 
UnknownTianlongkechuanling Inhibits Pulmonary Fibrosis Through Down-Regulation of Arginase-Ornithine Pathway.
Not available
S-EPMC8114272 | biostudies-literature
UnknownStructural and Biochemical Insights into Post-Translational Arginine-to-Ornithine Peptide Modifications by an Atypical Arginase.
Not available
S-EPMC10028609 | biostudies-literature
UnknownThe arginase 1/ornithine decarboxylase pathway suppresses HDAC3 to ameliorate the myeloid cell inflammatory response: implications for retinal ischemic injury.
Not available
S-EPMC10514323 | biostudies-literature
MetabolomicsUntargeted Metabolomics Reveals a Lack Of Synergy between Nifurtimox and Eflornithine against Trypanosoma brucei
A non-targeted metabolomics-based approach is presented that enables the study of pathways in response to drug action with the aim of defining the mode of action of trypanocides. Eflornithine, a polyamine pathway inhibitor, and nifurtimox, whose mode of action involves its metabolic activation, are ...
2017-06-07 | MTBLS459 | MetaboLights
UnknownCharacterisation of Expression the Arginine Pathway Enzymes in Childhood Brain Tumours to Determine Susceptibility to Therapeutic Arginine Depletion.
Not available
S-EPMC9242779 | biostudies-literature
UnknownThe mechanism of opiorphin-induced experimental priapism in rats involves activation of the polyamine synthetic pathway.
Not available
S-EPMC2770744 | biostudies-literature
UnknownThe Neighboring Subunit Is Engaged to Stabilize the Substrate in the Active Site of Plant Arginases.
Not available
S-EPMC7370999 | biostudies-literature
UnknownTranscriptional and Metabolomic Analysis of L-Arginine/Nitric Oxide Pathway in Inflammatory Bowel Disease and Its Association with Local Inflammatory and Angiogenic Response: Preliminary Findings.
Not available
S-EPMC7084352 | biostudies-literature
UnknownRelationship Between Plasma Osteopontin and Arginine Pathway Metabolites in Patients With Overt Coronary Artery Disease.
Not available
S-EPMC7424048 | biostudies-literature
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