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Abstract Protozoa of the genus Leishmania are the causative agents of leishmaniasis in humans. These parasites cycle between promastigotes in the sand fly mid-gut and amastigotes in phagolysosome of mammalian macrophages. During infection, they up-regulate host nitric oxide synthase and arginase exp...
ORGANISM(S): Leishmania donovani 
2016-04-11 | PXD002830 | Pride
Abstract Protozoa of the genus Leishmania are the causative agents of leishmaniasis in humans. These parasites cycle between promastigotes in the sand fly mid-gut and amastigotes in phagolysosome of mammalian macrophages. During infection, they up-regulate host nitric oxide synthase and arginase exp...
ORGANISM(S): Leishmania donovani 
2016-02-17 | PXD002766 | Pride
Metabolic stress caused by excess nutrients accelerates aging. We recently demonstrated that the newly discovered enzyme glycerol-3-phosphate phosphatase (G3PP; gene Pgp), which operates an evolutionarily conserved glycerol shunt that hydrolyzes glucose-derived glycerol-3-phosphate to glycerol, coun...
2024-02-07 | MTBLS6847 | MetaboLights
Protozoa of the genus Leishmania are the causative agents of leishmaniasis in humans. These parasites cycle between promastigotes in the sand fly mid-gut and amastigotes in phagolysosome of mammalian macrophages. During infection, host up-regulate nitric oxide synthase and parasite induce host argin...
ORGANISM(S): Leishmania donovani 
Arginine sensing (PRJCA036155)
RKO cell lysate proteins was pull down by arginine probe to find arginine binding protein
ORGANISM(S): Homo sapiens (Human) 
2025-05-01 | PXD063522 | Pride
Arginine sensing regulates virulence gene expression and disease progression in enteric pathogens.
Metabolic adaptation has recently been recognized as a key component of the intracellular life cycle of pathogenic microorganisms. Upon entry into mammalian host cells, Francisella tularensis, a pathogenic bacterium responsible for the zoonotic disease tularemia, rapidly escapes from the phagosome t...
ORGANISM(S): Francisella tularensis subsp. novicida (strain U112) 
2015-01-28 | PXD001584 | Pride
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