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TranscriptomicsMicroarray analysis of colonic mucosa biopsies in patients with inflammatory bowel disease
Microarrays were used to analyze the gene expression in endoscopic-derived intestinal mucosal biopsies from patients with inflammatory bowel disease (IBD) and controls Mucosal biopsies were obtained at endoscopy from the colon of 97 ulcerative colitis (UC), 8 Crohn's disease (CD) patients and 11 co...
ORGANISM(S): Homo sapiens 
2015-05-27 | E-GEOD-59071 | biostudies-arrayexpress
TranscriptomicsExpression data from normal and transplanted islets in non-pregnant and pregnant condition
ABSTRACT:Pregnancy requires a higher functional beta cell mass and this is associated with profound changes in the gene expression profile of pancreatic islets. Taking Tph1 as a sensitive marker for pregnancy-related islet mRNA expression in female mice, we previously identified prolactin receptors ...
ORGANISM(S): Mus musculus 
2015-03-31 | E-GEOD-59143 | biostudies-arrayexpress
TranscriptomicsMucosal expression profiling in patients with inflammatory bowel disease before and after first infliximab treatment
We used microarrays to identify mucosal gene signatures predictive of response to infliximab (IFX) in patients with inflammatory bowel disease (IBD) and to gain more insight into the pathogenesis of IBD. Keywords: drug response and treatment effect Mucosal biopsies were obtained at endoscopy in act...
ORGANISM(S): Homo sapiens 
2009-11-02 | E-GEOD-16879 | biostudies-arrayexpress
TranscriptomicsExpression data from islets of non-pregnant and pregnant PRLR+/+ and PRLR-/- mice
ABSTRACT:Pregnancy requires a higher functional beta cell mass and this is associated with profound changes in the gene expression profile of pancreatic islets. Taking Tph1 as a sensitive marker for pregnancy-related islet mRNA expression in female mice, we previously identified prolactin receptors ...
ORGANISM(S): Mus musculus 
2015-03-31 | E-GEOD-59141 | biostudies-arrayexpress
UnknownFull genome-based classification of rotaviruses reveals a common origin between human Wa-Like and porcine rotavirus strains and human DS-1-like and bovine rotavirus strains.
Not available
S-EPMC2268446 | biostudies-literature
TranscriptomicsColonic gene expression data of TIMP1 knock out colitis mice
Increased levels of tissue inhibitor of metalloproteinase-1 (TIMP-1) have been detected in fibrotic strictures in Crohn’s disease. In a murine model of chronic inflammation, fibrosis was associated with an increase in TIMP-1 and inhibition of matrix metalloproteinase (MMP)-mediated degradation. We...
ORGANISM(S): Mus musculus 
2016-07-22 | E-GEOD-73424 | biostudies-arrayexpress
TranscriptomicsColonic gene expression data of acute and chronic dextran sodium sulphate (DSS) colitis mice
The lack of suitable animal models reflecting chronically relapsing inflammation and tissue remodeling have hindered fibrosis research in inflammatory bowel diseases (IBD). This study investigated changes in connective tissue in a chronic murine model using different cycles of dextran sodium sulphat...
ORGANISM(S): Mus musculus 
2013-09-03 | E-GEOD-42768 | biostudies-arrayexpress
UnknownBiopsy-derived Intestinal Epithelial Cell Cultures for Pathway-based Stratification of Patients With Inflammatory Bowel Disease.
Not available
S-EPMC6443034 | biostudies-literature
UnknownCurrent Methodological Challenges of Single-Cell and Single-Nucleus RNA-Sequencing in Glomerular Diseases.
Not available
S-EPMC8455274 | biostudies-literature
UnknownIndications for distinct pathogenic mechanisms of asbestos and silica through gene expression profiling of the response of lung epithelial cells.
Not available
S-EPMC4402341 | biostudies-literature
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