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TranscriptomicsMycobacterium tuberculosis and macrophage response
This SuperSeries is composed of the following subset Series: GSE6209: The global transcriptional profile of Mycobacterium tuberculosis during human macrophages infection GSE7962: Sigma factor E of Mycobacterium tuberculosis controls the expression of bacterial components that modulate macrophages Ke...
ORGANISM(S): Mycobacterium tuberculosis 
2010-05-25 | E-GEOD-7963 | biostudies-arrayexpress
TranscriptomicsThe global transcriptional profile of Mycobacterium tuberculosis during human macrophages infection
During lung infection Mycobacterium tuberculosis (Mtb) resides in macrophages and subverts the bactericidal mechanisms of these professional phagocytes. In this work we have analyzed by DNA microarray technique the global transcription profile of Mtb infecting primary human macrophages in order to i...
ORGANISM(S): Mycobacterium tuberculosis 
2010-05-27 | E-GEOD-6209 | biostudies-arrayexpress
TranscriptomicsSigma factor E of Mycobacterium tuberculosis controls the expression of bacterial components that modulate macrophages
Sigma factor E (SigE) controls the expression of genes that are essential for Mtb virulence. In this work, we have identified the SigE regulon during infection of macrophages Our results indicate that SigE regulates the expression of genes involved in the maintenance of Mtb cell envelope integrity a...
ORGANISM(S): Mycobacterium tuberculosis 
2010-05-25 | E-GEOD-7962 | biostudies-arrayexpress
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