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UnknownAvelumab, an Anti-Programmed Death-Ligand 1 Antibody, In Patients With Refractory Metastatic Urothelial Carcinoma: Results From a Multicenter, Phase Ib Study.
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S-EPMC5493051 | biostudies-literature
TranscriptomicsEvaluation of the effects of shear stress on human dermal microvascular blood and lymphatic endothelial cells
The lymphatic system removes fluid from the interstitial space and returns it to the blood with a tremendous capacity: during inflammation, lymph flow rates can increase dramatically; however, during chronic lymphedema, there is little or no flow. The ability of lymphatic endothelium to sense and ac...
ORGANISM(S): Homo sapiens 
2009-11-30 | E-GEOD-8852 | biostudies-arrayexpress
TranscriptomicsMaintenance and resurrection of retinal pigmented epithelial cell phenotype by type 1 TGF-beta receptor kinase inhibitors
Age-related macular degeneration (AMD) is a leading cause of blindness. Most vision loss occurs following the transition from a disease of deposit formation and inflammation to a disease of neovascular fibrosis and/or cell death. Here, we investigate how protracted wound stimulus leads to seminal ch...
ORGANISM(S): Homo sapiens 
2015-07-06 | E-GEOD-62224 | biostudies-arrayexpress
TranscriptomicsReversal of persistent wound-induced retinal pigmented epithelial-to-mesenchymal transition by the TGFb pathway inhibitor, A-83-01.
Age-related macular degeneration (AMD) is a leading cause of blindness. Most vision loss occurs following the transition from a disease of deposit formation and inflammation to a disease of neovascular fibrosis and/or cell death. Here, we investigate how repeated wound stimulus leads to seminal chan...
ORGANISM(S): Homo sapiens 
2015-07-06 | E-GEOD-67898 | biostudies-arrayexpress
TranscriptomicsCross-talk between E. coli strains and a human colorectal adenocarcinoma-derived cell line
The deposit microarray data were generated in a study that comprehensively integrated gene expression profiles and metabolic responses of Caco-2 cells that incubated with either E. coli K-12 or O157:H7. The aim of this study is to examine the impact of colonic bacteria on the global gene expression ...
ORGANISM(S): Homo sapiens 
2013-08-23 | E-GEOD-50040 | biostudies-arrayexpress
GenomicsInduced Cdx2 binding in embryonic stem cells and endodermal cells
Regulatory proteins can bind to different sets of genomic targets in various cell types or conditions. To reliably characterize such condition-specific regulatory binding we introduce MultiGPS, an integrated machine learning approach for the analysis of multiple related ChIP-seq experiments. MultiGP...
ORGANISM(S): Mus musculus 
2014-03-27 | E-GEOD-39435 | biostudies-arrayexpress
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