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TranscriptomicsComparison of gene expression data from human and mouse breast cancers: Identification of conserved breast tumor genes
The aim of our work was the comparison of human and mouse gene expression data and to identify a conserved breast tumor gene set. The results encourage the usefulness of transgenic mice as a model for human breast cancer formation and therapy. Keywords: Comparison of gene expression data The aim of ...
ORGANISM(S): Homo sapiens 
2007-01-12 | E-GEOD-6596 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of rat neonatal ventricular cardiomyocytes (NRVCMs) stretched biaxially (112%/24h) or stimulated with phenylephrine (PE, 50 uM
Neonatal rat ventricular cardiomyocytes (NRVCMs) were stretched biaxially (112%/24h) or stimulated with phenylephrine (PE, 50 uM), both resulting in a similar degree of hypertrophy. Unstretched NRVCMs served as negative control. Affymetrix microarray analysis revealed 164 genes more than 2.0-fold up...
ORGANISM(S): Rattus norvegicus 
2008-06-14 | E-GEOD-5996 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human and mouse breast cancers
This SuperSeries is composed of the following subset Series:; GSE6581: Expression data from mammary glands of transgenic mice; GSE6596: Comparison of gene expression data from human and mouse breast cancers: Identification of conserved breast tumor genes Experiment Overall Design: Refer to individua...
ORGANISM(S): Homo sapiens 
2008-06-15 | E-GEOD-6772 | biostudies-arrayexpress
TranscriptomicsAffymetrix SNP array data for different passages of mesenchymal stem cells.
Cells in culture undergo replicative senescence and unequivocally stop proliferation after a limited number of cell divisions. In this study, we have expanded mesenchymal stem cells (MSC) from human adipose tissue and analyzed genetic and epigenetic sequels. The subpopulation of highly proliferative...
ORGANISM(S): Homo sapiens 
2013-02-15 | E-GEOD-27135 | biostudies-arrayexpress
TranscriptomicsProgression Free Survival in Ovarian Cancer is Reflected in Epigenetic DNA-Methylation Profiles
Objective: Many patients with ovarian cancer disease relapse within 6 months after adjuvant chemotherapy, with a limited prognosis. Epigenetic modifications have been shown to play an important role in tumor development and formation. Therefore, global analysis of DNA methylation patterns might reve...
ORGANISM(S): Homo sapiens 
2011-05-04 | E-GEOD-25033 | biostudies-arrayexpress
TranscriptomicsCharacterization of the miRNA profile of activated or apoptotic lymphocytes and corresponding released microvesicles in normal healthy donors and systemic lupus erythematosus (SLE) patients.
In this experiment, the miRNA profile of microvesicles (MV) released from activated or apoptotic (UV-B treated) T-lymphocytes and their cells of origin was analyzed in both samples obtained from normal healthy donors and systemic lupus erythematosus (SLE) patients. Therefore in short, RNA was isolat...
ORGANISM(S): Homo sapiens 
2018-03-31 | E-MTAB-3944 | biostudies-arrayexpress
TranscriptomicsNeisseria meningitidis elicits a pro-inflammatory response involving IM-NM-:BM-NM-6 in a human blood-cerebrospinal fluid barrier model.
The human-specific, Gram-negative bacterium Neisseria meningitidis (Nm) is a leading cause of bacterial meningitis world-wide. It has been described that Nm can enter the central nervous system via the blood-cerebrospinal fluid barrier (BCSFB), which is constituted by the epithelial cells of the cho...
ORGANISM(S): Homo sapiens 
2014-09-16 | E-GEOD-42870 | biostudies-arrayexpress
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