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Metabolism oscillates between catabolic and anabolic states depending on food intake, exercise, or stresses that change a multitude of metabolic pathways simultaneously. We present the HuMet Repository for exploring dynamic metabolic responses to oral glucose/lipid loads, mixed meals, 36-h fasting, ...
2024-07-23 | MTBLS89 | MetaboLights
Background: CrohnM-bM-^@M-^Ys disease is presently an incurable inflammatory bowel disease. Fistulae are extensions of the intestinal tract that may form connections with other organs. These are a common complication of CrohnM-bM-^@M-^Ys disease affecting up to 50% of patients with the most common i...
ORGANISM(S): Homo sapiens 
Asymmetric dimethylarginine (ADMA) is a naturally occurring inhibitor of nitric oxide synthesis that accumulates in wide range of diseases associated with endothelial dysfunction and enhanced atherosclerosis. Plasma ADMA has been implicated as a major novel cardiovascular risk factor, but the mechan...
ORGANISM(S): Homo sapiens 

Study to evaluate the molecular genetics of ccRCC through integrative analyses of tumors and tumorgrafts using multiple platforms in clinically annotated samples. Genome and exome data for patients giving consent to have the information available on a public, secure, database is being submitted.<...

A time-course experiment was performed: HUVECs were exposed for 2, 4, 8 and 24 hours to (Z)-1-[N-(2-aminoethyl)-N-(2-ammonioethyl)amino]diazen-1-ium-1,2-diolate (DETA-NONOate) 250 uM.
ORGANISM(S): Homo sapiens 
HUVEC were exposed to 1 mM sodium nitroprusside (SNP) for 2, 4, 8 and 24 hours and compared to untreated control cells.
ORGANISM(S): Homo sapiens 
HUVEC were exposed to 0.1, 1 and 10 mM sodium nitroprusside (SNP) for 4 hours and compared to untreated control cells.
ORGANISM(S): Homo sapiens 
HUVECs were exposed to 250 uM DETA-NONOate for 4 hours in the presence and absence of 10 uM of the guanylate cyclase inhibitor 1H-[1,2,4]oxadiazolo-[4,3,2]quinoxalin-1-one (ODQ). Control cells were exposed to vehicle (methanol 0.1%).
ORGANISM(S): Homo sapiens 
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