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TranscriptomicsArgonaute proteins couple chromatin silencing to alternative splicing (RNA IP-Seq)
While Argonaute (AGO) proteins play a major role in transcriptional gene silencing (TGS) in many organisms, their role in the nucleus of somatic mammalian cells remains elusive. Here, we have purified AGO1 and AGO2 chromatin-embedded complexes, and found these proteins associated with previously des...
ORGANISM(S): Homo sapiens 
2012-09-10 | E-GEOD-39748 | biostudies-arrayexpress
TranscriptomicsThe impact of experience-dependent and independent factors on gene expression in songbird brain [e04]
Songbirds provide rich natural models for studying the relationships of brain anatomy, behavioral function, environmental signals and gene expression. Under the Songbird Neurogenomics Initiative, investigators from more than a dozen laboratories collected brain samples from six species of songbird ...
ORGANISM(S): Taeniopygia guttata 
2012-05-30 | E-GEOD-36708 | biostudies-arrayexpress
TranscriptomicsArgonaute proteins couple chromatin silencing to alternative splicing
This SuperSeries is composed of the following subset Series: GSE39746: Argonaute proteins couple chromatin silencing to alternative splicing (exon array) GSE39748: Argonaute proteins couple chromatin silencing to alternative splicing (RNA IP-Seq) Refer to individual Series
ORGANISM(S): Mus musculus 
2012-08-22 | E-GEOD-39749 | biostudies-arrayexpress
UnknownOutcome after relapse of myelodysplastic syndrome and secondary acute myeloid leukemia following allogeneic stem cell transplantation: a retrospective registry analysis on 698 patients by the Chronic Malignancies Working Party of the European Society of Blood and Marrow Transplantation.
Not available
S-EPMC5792268 | biostudies-literature
UnknownRare de novo gain-of-function missense variants in DOT1L are associated with developmental delay and congenital anomalies.
Not available
S-EPMC10645550 | biostudies-literature
TranscriptomicsPRPF8 CLIP seq for iPSC, kidney organoid, retinal organoid, and retinal epithelium derived from c.6926A>C RPE with Retinitis Pigmentosa patients and CRISPR/Cas9 corrected
Retinitis Pigmentosa is a group of inherited eye disorders characterized by progressive degeneration of photoreceptor cells in the retina, leading to vision loss and eventual blindness. One of the known genetic mutations associated with RP is the c.6926A>C mutation in the RPE (retinal pigment epithe...
ORGANISM(S): Homo sapiens 
2024-03-13 | E-MTAB-13171 | biostudies-arrayexpress
TranscriptomicsRole of SPI-1 Secreted Effectors, SipA, SopABDE2, in Acute Bovine Response to Salmonella enterica Serovar Typhimurium
Salmonella enterica Serovar Typhimurium (S. Typhimurium) causes enterocolitis in humans and calves characterized by diarrhea and polymorphonuclear cell (PMN) influx to the intestinal mucosa. The Salmonella Type III Secretion System encoded at Pathogenicity Island I (SPI-1) translocates the Salmonel...
ORGANISM(S): Bos taurus 
2012-01-10 | E-GEOD-13847 | biostudies-arrayexpress
TranscriptomicsThe impact of experience-dependent and independent factors on gene expression in songbird brain [e07]
Songbirds provide rich natural models for studying the relationships of brain anatomy, behavioral function, environmental signals and gene expression. Under the Songbird Neurogenomics Initiative, investigators from more than a dozen laboratories collected brain samples from six species of songbird ...
ORGANISM(S): Taeniopygia guttata 
2012-05-30 | E-GEOD-36712 | biostudies-arrayexpress
TranscriptomicsImmune status, strain background, and anatomic site of innoculation affect mouse papillomavirus (MmuPV1) induction of exophytic papillomas or endophytic trichoblastomas
Papillomaviruses (PVs) are able to induce papillomas, premalignant lesions, and carcinomas in a wide variety of species. PVs are classified first based on their host and tissue tropism and then their genomic diversities. A laboratory mouse papillomavirus, MmuPV1 (formerly MusPV), naturally infects N...
ORGANISM(S): Mus musculus 
2014-10-28 | E-GEOD-58094 | biostudies-arrayexpress
TranscriptomicsGene expression data for worker honey bees experimentally exposed to a dual infection with Deformed wing virus and Nosema ceranae.
Bees from 3 unrelated colonies were injected with 1ul PBS extract containing 10^9 genome equivalent of Deformed wIng virus (DWV) and/or fed 10µl sucrose solution containing 10^5 fresh Nosema ceranae spores. Control bees were injected and fed with an equivalent DWV- and Nosema-free extract respectiv...
ORGANISM(S): Apis mellifera 
2017-03-08 | E-MTAB-5508 | biostudies-arrayexpress
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