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TranscriptomicsAn ABA response regulator unique to basal land plants required for the acquisition of desiccation tolerance
Purpose: The plant hormone abscisic acid (ABA) coordinates responses leading to desiccation tolerance in all land plants. RNA-seq was employed to obtain differential expression data in response to ABA, dehydration and mannitol treatments in wild-type tissue. This was compared against the targeted ge...
ORGANISM(S): Physcomitrella patens 
2016-07-25 | E-GEOD-72583 | biostudies-arrayexpress
MetabolomicsAntiviral metabolite 3'-Deoxy-3',4'-didehydro-cytidine is detectable in serum and identifies acute viral infections including COVID-19

BACKGROUND: There is a critical need for rapid viral infection diagnostics to enable prompt case identification in pandemic settings and support targeted antimicrobial prescribing.

METHODS: Using untargeted high-resolution liquid chromatography coupled with...

2022-02-10 | MTBLS718 | MetaboLights
TranscriptomicsTranscription profiling of rat neonatal ventricular cardiomyocytes (NRVCMs) stretched biaxially (112%/24h) or stimulated with phenylephrine (PE, 50 uM
Neonatal rat ventricular cardiomyocytes (NRVCMs) were stretched biaxially (112%/24h) or stimulated with phenylephrine (PE, 50 uM), both resulting in a similar degree of hypertrophy. Unstretched NRVCMs served as negative control. Affymetrix microarray analysis revealed 164 genes more than 2.0-fold up...
ORGANISM(S): Rattus norvegicus 
2008-06-14 | E-GEOD-5996 | biostudies-arrayexpress
TranscriptomicsTranscriptome sequencing and comparative transcriptome analysis of the scleroglucan producer Sclerotium rolfsii
Two S. rolfsii transcriptomes obtained from scleroglucan-producing and scleroglucan-nonproducing conditions were pooled and sequenced using the 454 pyrosequencing technique yielding ~350,000 reads. These could be assembled into 21,937 contigs and 171,833 singletons, for which 6,951 had significant m...
ORGANISM(S): Athelia rolfsii 
2010-05-15 | E-GEOD-21040 | biostudies-arrayexpress
TranscriptomicsTranscription profiling by array of human female interstitial cystitis urothelial cells after inducing differentiation
Purpose: Evaluate gene expression profiles after inducing differentiation in cultured interstitial cystitis (IC) and control urothelial cells. Materials and Methods: Bladder biopsies were taken from IC patients and controls (women having surgery for stress incontinence). Primary cultures were gro...
ORGANISM(S): Homo sapiens 
2008-10-25 | E-GEOD-11839 | biostudies-arrayexpress
UnknownRuxolitinib in corticosteroid-refractory graft-versus-host disease after allogeneic stem cell transplantation: a multicenter survey.
Not available
S-EPMC4854652 | biostudies-literature
TranscriptomicsTranscriptomic profiling of chicken adipose tissue of domestic chickens
Domestic chicken has been intensively studied because of its role as an efficient source of lean meat. However, commercial broilers resulting from genetic selection for rapid growth demonstrate detrimental traits, such as excess deposition of abdominal adipose tissue, metabolic disorders, and reduce...
ORGANISM(S): Gallus gallus 
2013-12-23 | E-GEOD-44394 | biostudies-arrayexpress
UnknownEfficacy and Safety of HLD200, Delayed-Release and Extended-Release Methylphenidate, in Children with Attention-Deficit/Hyperactivity Disorder.
Not available
S-EPMC5567875 | biostudies-literature
UnknownSynthesis and metalation of polycatechol nanohoops derived from fluorocycloparaphenylenes.
Not available
S-EPMC10510647 | biostudies-literature
UnknownFinal Analysis of Efficacy and Safety of Single-Dose Ad26.COV2.S.
Not available
S-EPMC8849184 | biostudies-literature
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