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The effects of the CDK inhibitors PHA-848125 and PHA-690509 on the A2780 cell line were analysed by gene expression profiling. The A2780 cell line was treated with PHA-848125 (CDk-125) or PHA-690509 (CDk-509) for 6 hours at a dose equal to 5 times the IC50. Untreated A2780 cells were used as a contr...
ORGANISM(S): Homo sapiens 
Understanding toxicity pathways of engineered nanomaterials (ENM) has recently been brought forward as a key step in 21st century ENM risk assessment. Molecular mechanisms linked to phenotypic end points is a step towards the development of toxicity tests based on key events, which may allow for gro...
ORGANISM(S): Homo sapiens 
Expression profiling of forager brains as a function of individual genotype (AHB/EHB) and environment (AHB/EHB host colony)
ORGANISM(S): Apis mellifera 
Expression profiling of guards brains as a function of individual genotype (AHB/EHB) and environment (AHB/EHB host colony)
ORGANISM(S): Apis mellifera 
Expression profiling of soldiers brains as a function of individual genotype (AHB/EHB) and environment (AHB/EHB host colony)
ORGANISM(S): Apis mellifera 
Adipose-derived and bone-marrow-derived mesenchymal stem cells were collected from 3 pigs and cultivated in vitro up to 3 passages. At passage 3 cells were cultured to 80% confluence and induced to differentiate in adipose and bone. Cell were harvested at 0 day of differentiation (dd) or pre-differe...
ORGANISM(S): Sus scrofa 
Microbe associated molecular pattern (MAMP)-responsive genes were identified in leaves of four different genotypes. The genotypes used in this study were: LD0-2817P; LDX01-1-65; Ripley and EF59. Leaves from three-weeks old plants were used in this study We used microarray to identified the MAMP-resp...
ORGANISM(S): Glycine max 
We analyzed the changes in brain gene expression after alarm pheromone exposure. Bees from single-drone inseminated colonies were exposed to alarm pheromone at the hive entrance and collected 1h after exposure for analysis.
ORGANISM(S): Apis mellifera 
Scouts and non-scouts (recruits) were collected by using a novelty-seekingM-^] assay. Experiment was conducted in a large outdoor screened enclosure, which enabled us to exert complete control over the location and number of food resources while at the same time studying naturalistic honey bee forag...
ORGANISM(S): Apis mellifera 
Bees were trained to visit food sources at different times of day. By collecting bees just before the training times, we were able to analyze the genes that are associated with the time of day, the time of training, the activity state, or genes associated with unique spatiotemporal memories
ORGANISM(S): Apis mellifera 
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