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TranscriptomicsExpression Differences in Ethanol Stress Response Between Saccharomyces cerevisiae Parent W303-1A Strain and its Two Ethanol Tolerant Mutants
Saccharomyces spp. are widely used for ethanol production however fermentation productivity is negatively affected by the impact of ethanol accumulation on yeast metabolic rate and viability. This study used microarray and statistical two-way ANOVA analysis to compare and evaluate gene expression pr...
ORGANISM(S): Saccharomyces cerevisiae 
2010-07-01 | E-GEOD-21120 | biostudies-arrayexpress
TranscriptomicsRole of SPI-1 Secreted Effectors, SipA, SopABDE2, in Acute Bovine Response to Salmonella enterica Serovar Typhimurium
Salmonella enterica Serovar Typhimurium (S. Typhimurium) causes enterocolitis in humans and calves characterized by diarrhea and polymorphonuclear cell (PMN) influx to the intestinal mucosa. The Salmonella Type III Secretion System encoded at Pathogenicity Island I (SPI-1) translocates the Salmonel...
ORGANISM(S): Bos taurus 
2012-01-10 | E-GEOD-13847 | biostudies-arrayexpress
TranscriptomicsGlobal Analysis of Yeast mRNPs
Proteins regulate gene expression by controlling mRNA biogenesis, localization, translation and decay. Identifying the composition, diversity and function of mRNPs (mRNA protein complexes) is essential to understanding these processes. In a global survey of S. cerevisiae mRNA binding proteins we ide...
ORGANISM(S): Saccharomyces cerevisiae 
2013-04-18 | E-GEOD-46142 | biostudies-arrayexpress
TranscriptomicsGenome-wide analysis reveals conserved transcriptional responses downstream of resting potential change in Xenopus embryos, axolotl regeneration, and human mesenchymal cell differentiation [human data]
Endogenous bioelectric signaling via changes in cellular resting potential (Vmem) is a key regulator of patterning during regeneration and embryogenesis in numerous model systems. Depolarization of Vmem has been functionally implicated in de-differentiation, tumorigenesis, anatomical re-specificatio...
ORGANISM(S): Homo sapiens 
2016-07-03 | E-GEOD-72098 | biostudies-arrayexpress
TranscriptomicsComparative analysis of genes regulated by Dzip1/iguana and Hedgehog in zebrafish
The morphogen Sonic H edgehog governs a wide range of developmental processes. The zebrafish genetic mutant iguana has vascular stability defects due to decreased Shh signaling. Using iguana mutant embryos and embryos treated with the Hedgehog pathway inhibitor cyclopamine, we conducted a microarray...
ORGANISM(S): Danio rerio 
2014-06-30 | E-GEOD-48335 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of two transgenic models familial hypertrophic cardiomyopathy mice vs wild type and non transgenic controls using pooled and non pooled heart extracts to identify differences in gene expression in FHC
Familial hypertrophic cardiomyopathy (FHC) is a disease characterized by ventricular hypertrophy, fibrosis, and aberrant systolic and/or diastolic function. We previously developed two transgenic mouse models that carry FHC associated mutations in alpha-tropomyosin (TM): FHC alpha-TM175 mice show pa...
ORGANISM(S): Mus musculus 
2007-11-23 | E-GEOD-4678 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human monocyte-derived macrophages infected with HIV-1 or uninfected and stimulated with E. coli lipopolysaccharide
Whole genome expression profiling of HIV-1 infected and uninfected monocyte-derived macrophages
ORGANISM(S): Homo sapiens 
2009-01-01 | E-MEXP-1904 | biostudies-arrayexpress
UnknownEuropean screening platform for EORTC clinical trials in advanced colorectal cancer 'SPECTAcolor'.
Not available
S-EPMC12836792 | biostudies-literature
TranscriptomicsMicroarray analysis of human umbilical vein endothelial cells (HUVECs) chronically irradiated with low dose-rate of ionizing radiation for one, three and six weeks.
To obtain more insight in the molecular effects of chronic low dose irradiation on endothelial cells, HUVEC were irradiated with low-dose rate irradiation (137Cs gamma source; 0, 1.4 and 4.1 mGy/h) for several weeks. At different time points (1, 3 and 6 weeks) cells were harvested for RNA extraction...
ORGANISM(S): Homo sapiens 
2018-02-28 | E-MTAB-6521 | biostudies-arrayexpress
UnknownBacille Calmette-Guerin vaccination to prevent febrile and respiratory illness in adults (BRACE): secondary outcomes of a randomised controlled phase 3 trial.
Not available
S-EPMC11106519 | biostudies-literature
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