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TranscriptomicsMicroRNA expression from ARPE-19 cells: control and PDTC treated.
The cultured cell line ARPE-19 is frequently employed in studies of rpe function. Here we have identified the microRNAs expressed in RPE cells in the presence and absence of PDTC (pyrrolidine dithiocarbamate), an antioxidant. Analysis used microrNA extracted from untreated cells as a control for ce...
ORGANISM(S): Homo sapiens 
2010-07-24 | E-GEOD-23107 | biostudies-arrayexpress
TranscriptomicsExpression data from ARPE-19 cells treated with LDL or ox-LDL
LDL or Ox-LDL 200ug/ml, which showed no loss of viability after a 48 hour exposure, induced a physiological and pathological transcriptional response, respectively. LDL induced a downregulation of genes associated with cholesterol biosynthesis while ox-LDL induced transcriptional alterations in gene...
ORGANISM(S): Homo sapiens 
2006-09-01 | E-GEOD-5741 | biostudies-arrayexpress
TranscriptomicsExpression Data from DMSO or SRPIN803 treated ARPE-19 cells
We used microarrays to evaluate the effect of SRPIN803 on gene expression in ARPE-19 cells. ARPE-19 cells were treated with SRPIN803 (10 uM) or the negative control (0.1% DMSO) for 4 hours for Total RNA isolation and hybridization on Microarray.
ORGANISM(S): Homo sapiens 
2015-06-17 | E-GEOD-62947 | biostudies-arrayexpress
TranscriptomicsUntreated and iron-treated ARPE-19 cell gene expression
To characterize the potential molecular pathway(s) affected by iron treatment and identify the one(s) responsible for C3 induction, we performed a whole genome microarray on untreated ARPE-19 cells and cells treated with 250 ?M FAC for 48h/2d. Gene expression was compared between untreated and FAC-t...
ORGANISM(S): Homo sapiens 
2015-04-07 | E-GEOD-67603 | biostudies-arrayexpress
TranscriptomicsGene expression profiling/transcription analyses of ARPE-19 cells after docosahexaenoic acid treatment
A global gene expression profiling of ARPE-19 cells after supplementation of DHA or vehicle for 1, 3, 6, 12 and 24 h to determine differentially expressed transcripts.
ORGANISM(S): Homo sapiens 
2014-10-31 | E-MTAB-3016 | biostudies-arrayexpress
TranscriptomicsMicroarray of human ARPE-19 cells treated with Cochlin recombinant protein
Study the gene expression profiling of human retinal pigmented epithelium cell line ARPE-19 treated with or without human recombinant Cochlin protein for 24 hours.
ORGANISM(S): Homo sapiens 
2023-05-05 | E-MTAB-12364 | biostudies-arrayexpress
ProteomicsData-Independent Proteome Analysis of ARPE-19 Cells
We have performed a proteomics analysis of a human retinal pigment epithelial cell line (ARPE-19), which represents a widely used model for in vitro studies of cellular and molecular mechanisms related to human RPE cells. The project was jointly supervised by Francesco Giorgianni and Sarka...
ORGANISM(S): Homo sapiens (Human) 
2018-04-26 | PXD009607 | Pride
Rpe cells  data-independent  label-free quantification 
TranscriptomicsChemokine expression in retinal pigment epithelial cells in response to co-culture with activated T Cells
Purpose: To investigate the effects of T cell-derived cytokines on gene and protein expression of chemokines in a human RPE cell line (ARPE-19). Methods: We used an in vitro co-culture system in which the RPE and CD3/28-activated T cells were separated by a membrane. Differential gene expression in...
ORGANISM(S): Homo sapiens 
2012-11-19 | E-GEOD-36331 | biostudies-arrayexpress
ProteomicsQuantitative proteomic analysis of ARPE-19 cells in response to LPS
Overwhelming and persistent inflammation of retinal pigment epithelium (RPE) induces destructive changes in retinal environment by invoking immune activation. In this study, we aimed to investigate RPE-specific biological and metabolic response against intense inflammation, and identify molecular ch...
ORGANISM(S): Homo sapiens (Human) 
2021-09-09 | PXD018257 | Pride
Lps Arpe-19 Human 
ProteomicsQuantitative phosphoproteomic analysis of ARPE-19 cells in response to LPS
Overwhelming and persistent inflammation of retinal pigment epithelium (RPE) induces destructive changes in retinal environment by invoking immune activation. In this study, we aimed to investigate RPE-specific biological and metabolic response against intense inflammation, and identify molecular ch...
ORGANISM(S): Homo sapiens (Human) 
2021-09-09 | PXD018260 | Pride
Lps Arpe-19 Human 
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