Sort   by:  
 Page size 
ProteomicsCDKL1 risk variants predispose to a connective tissue disorder with thoracic aortic aneurysm and dissection
Genetic factors are fundamental in the etiology of thoracic aortic aneurysm and dissection (TAAD), but the genetic cause is detected in only about 30% of cases. To define unreported TAAD-associated sequence variants, exome and gene panel sequencing was performed in 323 patients. We identified hetero...
ORGANISM(S): Homo sapiens (Human) 
2025-09-09 | PXD048044 | Pride
Cdkl1 Cgmp signaling Thoracic aortic aneurysm and dissection Arterial aneurysm and dissection Hereditary aortopathy Connective tissue disorder 
TranscriptomicsTranscription profiling of aorta from mice underexpressing Fibulin-4 to investigate its role in elastic fibre assembly and cardio-vasuclar disease
Extracellular elastic fibres apply structure and mechanical elasticity to organs such as large arteries, lungs and skin 1. Elastic fibres are assembled through polymerization of tropoelastin monomers and loss of elastin is associated with aneurysmal degeneration of the aorta 2. The Fibulins are a ...
ORGANISM(S): Mus musculus 
2007-01-01 | E-MEXP-840 | biostudies-arrayexpress
UnknownAngiogenesis Inhibitors and Arterial Dissection or Aneurysm in Patients With Metastatic Colorectal Cancer.
Not available
S-EPMC12679322 | biostudies-literature
UnknownNovel LOX Variants in Five Families with Aortic/Arterial Aneurysm and Dissection with Variable Connective Tissue Findings.
Not available
S-EPMC8269155 | biostudies-literature
UnknownCausal association between dietary habits and aortic dissection and aortic aneurysm: Mendelian randomization study.
Not available
S-EPMC12863792 | biostudies-literature
UnknownClinical course of conservative management for isolated superior mesenteric arterial dissection.
Not available
S-EPMC6538844 | biostudies-literature
UnknownMatrix Metalloproteinase in Abdominal Aortic Aneurysm and Aortic Dissection.
Not available
S-EPMC6789891 | biostudies-literature
TranscriptomicsTenascin C prevents acute aortic dissection in mice
Acute aortic dissection (AAD) is one of the major aortic diseases that occurs without a preceding symptom and often results in sudden death. Despite the recent advances in cardiovascular medicine, AAD remains a serious problem because its molecular pathogenesis is largely unknown. In this paper, w...
ORGANISM(S): Mus musculus 
2015-03-27 | E-GEOD-36899 | biostudies-arrayexpress
UnknownInducing aortic aneurysm/dissection in zebrafish: evaluating the efficacy of β-Aminopropionic Nitrile as a model.
Not available
S-EPMC10911251 | biostudies-literature
UnknownDifferential cell-matrix mechanoadaptations and inflammation drive regional propensities to aortic fibrosis, aneurysm or dissection in hypertension.
Not available
S-EPMC5721146 | biostudies-literature
Sort   by:  
 Page size