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TranscriptomicsGene expression profiling of murine innate lymphoid cells
Innate lymphoid cells (ILCs) are a recently recognized heterogenous group of immune cells that are critical in orchestrating immunity and inflammation in the intestine, but whether ILCs influence immune responses or tissue homeostasis at other mucosal sites remains poorly characterized. Here we iden...
ORGANISM(S): Mus musculus 
2013-04-30 | E-GEOD-46468 | biostudies-arrayexpress
TranscriptomicsGene expression profiling of macrophages from conventional or antibiotic-treated mice
Antibiotic-treated (ABX) mice exhibit an impaired innate and adaptive antiviral immune response and substantially delayed viral clearance following exposure to systemic LCMV or mucosal influenza virus. Genome-wide transcriptional profiling of macrophages isolated from ABX mice revealed decreased ex...
ORGANISM(S): Mus musculus 
2015-11-05 | E-GEOD-74712 | biostudies-arrayexpress
TranscriptomicsRegulation of gene expression in IECs by HDAC3 under germ-free conditions
The development and severity of inflammatory bowel diseases (IBD) and other chronic inflammatory conditions can be influenced by host genetic and environmental factors, including signals derived from commensal bacteria. However, the mechanisms that integrate these diverse cues remain undefined. Her...
ORGANISM(S): Mus musculus 
2013-11-12 | E-GEOD-50189 | biostudies-arrayexpress
TranscriptomicsRegulation of gene expression in IECs by HDAC3
The development and severity of inflammatory bowel diseases (IBD) and other chronic inflammatory conditions can be influenced by host genetic and environmental factors, including signals derived from commensal bacteria. However, the mechanisms that integrate these diverse cues remain undefined. Her...
ORGANISM(S): Mus musculus 
2013-11-12 | E-GEOD-50188 | biostudies-arrayexpress
TranscriptomicsGene expression profiling of naïve bone marrow-resident granulocyte monocyte precursors (GMPs) and TSLP-elicited splenic GMP-like cells
Extramedullary hematopoiesis (EMH) refers to the differentiation of hematopoietic stem cells (HSCs) into effector cells that occurs in compartments outside of the bone marrow. Previous studies linked pattern recognition receptor (PRR)-expressing HSCs, EMH and immune responses to microbial stimuli. H...
ORGANISM(S): Mus musculus 
2014-03-28 | E-GEOD-52485 | biostudies-arrayexpress
GenomicsHDAC3-dependent regulation of H3K9 acetylation in IECs
The development and severity of inflammatory bowel diseases (IBD) and other chronic inflammatory conditions can be influenced by host genetic and environmental factors, including signals derived from commensal bacteria. However, the mechanisms that integrate these diverse cues remain undefined. Her...
ORGANISM(S): Mus musculus 
2013-12-02 | E-GEOD-50453 | biostudies-arrayexpress
GenomicsHistone Deacetylase 3 is an Epigenomic Brake in Macrophage Alternative Activation (ChIP-Seq)
We report the genomic regions enriched in Histone Deacetylase 3 (HDAC3) in mouse bone marrow derived macrophages. Furthermore, we also report the genomic acetylation pattern on Histone 3, Lysine 9 (H3K9) in macrophages with and without HDAC3 and/or treated with Th2 cytokine IL-4. HDAC3 enriched gen...
ORGANISM(S): Mus musculus 
2011-11-10 | E-GEOD-33596 | biostudies-arrayexpress
Proteomicshigh fiber diet mice methanol extracts
comparison between high fiber diet and ctrl mice methanol extraction, q exactive hf, 28 min method
ORGANISM(S): Mus Sp. (ncbitaxon:10095) 
2021-02-16 | MSV000086890 | MassIVE
UnknownHost metabolism balances microbial regulation of bile acid signalling.
Not available
S-EPMC11886927 | biostudies-literature
MetabolomicsGNPS - high fiber diet mice methanol extracts
comparison between high fiber diet and ctrl mice methanol extraction, q exactive hf, 28 min method
ORGANISM(S): Mus Sp. (ncbitaxon:10095) 
2021-02-16 | MSV000086890 | GNPS
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