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TranscriptomicsMixed-polarization phenotype of ascites-associated macrophagesin human ovarian carcinoma: correlation of CD163 expression, cytokine levels and early relapse
Ascites-associated macrophages were collected from human ovarian carcinoma patients and their expression profiles determined via Agilent microarrays. In addition, monocyte derived macrophages from healthy donors were differentiated ex-vivo with MCSF and GMCSF and their expression profiles determined...
ORGANISM(S): Homo sapiens 
2014-03-07 | E-MTAB-1661 | biostudies-arrayexpress
ProteomicsProteome profiling of ovarian cancer and cirrhosis ascites
Proteome-metabolome profiling of ovarian cancer ascites reveals novel components involved in intercellular communication http://www.mcponline.org/content/early/2014/09/30/mcp.M114.041194.full.pdf+html?sid=78e7a955-fa54-4ded-b296-89f1fb6adbec
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2016-07-19 | MSV000079934 | MassIVE
TranscriptomicsAscites enriches for ovarian cancer stem-like cells that express membrane GRP78
Ovarian cancer patients are generally diagnosed at stage III/IV, when ascites is common. The volume of ascites positively correlates with the extent of metastasis and negatively with prognosis. Membrane GRP78, a stress-inducible endoplasmic reticulum chaperone which also appears on the plasma membra...
ORGANISM(S): Mus musculus 
2015-03-09 | E-GEOD-61285 | biostudies-arrayexpress
ProteomicsGlycomic and proteomic analyses of malignant ascites fluid were used to identify potential metastatic biomarkers of epithelial ovarian cancer : Partial
Ovarian cancer is a major cause of cancer mortality among women largely due to late diagnosis of advanced stage metastatic disease. More extensive molecular analysis of metastatic ovarian cancer is needed to identify post-translational modifications of proteins particularly associated with metastati...
ORGANISM(S): Homo sapiens (Human) 
2016-08-15 | PXD003794 | Pride
Ascites Concanavalin a Epithelial ovarian cancer 
ProteomicsGastric cancer ascites proteome
Gastric cancer is one of the most lethal malignancies with high mortality and gastric cancer-specific biomarker is need due to the lack of specific method for early screening, diagnosis, and prognosis of the patients with gastric cancer. Ascites is known for an important source for conducing biomark...
ORGANISM(S): Homo sapiens (Human) 
2018-04-16 | PXD002213 | Pride
Proteome profiling Proteomics Ascites Gastric cancer Biomarker 
GenomicsChIP-seq of tumour associated macrophages derived from high grade ovarian serous carcinoma patient ascites
Tumor associated macrophages of one patient were assayed for histone modifications, methylation (MIRA) and CEBP.
ORGANISM(S): Homo sapiens 
2018-08-13 | E-MTAB-6297 | biostudies-arrayexpress
ProteomicsProteome profiles of paired ovarian cancer ascites before and after chemotherapy
Ovarian cancer is characterized by transcoelomic metastasis into the peritoneal cavity. The peritoneal malignant ascites is enriched with ovarian cancer cells and a small amount of tumor-associated immune cells which create a unique microenvironment actively contributing to progression of the diseas...
ORGANISM(S): Homo sapiens (Human) 
2024-05-29 | PXD019327 | Pride
Ovarian cancer ascites Combinatorial peptide libraries Therapy-induced secretome 
ProteomicsIn-depth proteome analysis of human ascites using high-pH peptide fractionation
For in-depth profiling, ascites from patients with benign disease or gastric cancer were subjected to high-resolution mass spectromtery analysis. By high-pH peptide fractionation, 3481 protein groups were identified in 72 LC-MS/MS runs.
ORGANISM(S): Homo sapiens (Human) 
2018-04-16 | PXD003351 | Pride
Ascites High-ph peptide fractionation Gastric cancer 
TranscriptomicsRole of malignant ascites on human mesothelial cells and their gene expression profiles
Background: Malignant ascites is often present at diagnostic in women with advanced ovarian cancer (OC) and its presence is associated with a worse outcome. Human peritoneal mesothelial cells (HPMCs) are key components of malignant ascites. Although the interplay between HPMCs and OC cells is believ...
ORGANISM(S): Homo sapiens 
2014-04-14 | E-GEOD-55065 | biostudies-arrayexpress
ProteomicsPeptidome profiling of ovarian cancer and non-cancer proximal fluids: ascites and blood sera
Ovarian cancer is the most lethal gynecological malignancy, because its early detection is difficult due to the absence of recognizable physical symptoms and a lack of sensitive screening methods. Despite a large number of proteomic studies of biological fluids from ovarian cancer patients, only a f...
ORGANISM(S): Homo sapiens (Human) 
2018-04-05 | PXD009382 | Pride
Blood sera Ovarian cancer Ascites Peptidome 
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