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GenomicsNeuroligin-3 R451C Induces Gain-of-Function Gene Expression in Astroglia in an Astroglia-Enriched Brain Organoid Model
Neuroligin-3 R451C Induces Gain-of-Function Gene Expression in Astroglia in an Astroglia-Enriched Brain Organoid Model
PRJNA1194041 | ENA
GenomicsCortical astroglia transcriptomic dysregulation in the G93A SOD1 ALS mouse model
Cortical astroglia transcriptomic dysregulation in the G93A SOD1 ALS mouse model
PRJNA435616 | ENA
GenomicsEffects of inflammation on human astroglia in 3D cultures
Effects of inflammation on human astroglia in 3D cultures
PRJNA1118774 | ENA
TranscriptomicsNeuroligin-3 R451C Induces Gain-of-Function Gene Expression in Astroglia in an Astroglia-Enriched Brain Organoid Model
Astroglia are integral to brain development and the emergence of neurodevelopmental disorders. However, studying the pathophysiology of human astroglia using brain organoid models has been hindered by inefficient astrogliogenesis. In this study, we introduce a robust method for generating astroglia-...
ORGANISM(S): Homo sapiens 
2024-12-08 | GSE283484 | GEO
TranscriptomicsCortical astroglia transcriptomic dysregulation in the G93A SOD1 ALS mouse model
Astroglia are the most abundant cell type in the central nervous system. They play essential roles in the homeostasis of the CNS. Astroglia are extremely diverse. In Amyotrophic Lateral Sclerosis (ALS) astroglia in spinal cord undergo dramatic transcriptomic dysregulation. However there is little to...
ORGANISM(S): Mus musculus 
2019-04-30 | GSE111031 | GEO
TranscriptomicsA Transcriptome Database for Astrocytes, Neurons, and Oligodendrocytes
A Transcriptome Database for Astrocytes, Neurons, and Oligodendrocytes: A New Resource for Understanding Brain Development and Function Understanding the cell-cell interactions that control CNS development and function has long been limited by the lack of methods to cleanly separate astrocytes, neu...
ORGANISM(S): Mus musculus 
2007-12-30 | E-GEOD-9566 | biostudies-arrayexpress
UnknownStem and Progenitor Cell-Derived Astroglia Therapies for Neurological Diseases.
Not available
S-EPMC4637244 | biostudies-literature
UnknownMolecularly defined cortical astroglia subpopulation modulates neurons via secretion of Norrin.
Not available
S-EPMC6551209 | biostudies-literature
UnknownCortical astroglia undergo transcriptomic dysregulation in the G93A SOD1 ALS mouse model.
Not available
S-EPMC6444185 | biostudies-literature
GenomicsDual and separable roles for Ezh2 in neurogenic astroglia
The epigenetic mechanisms that enable specialized astrocytes to retain neurogenic competence throughout adult life are still poorly understood. Here we show that astrocytes that serve as neural stem cells (NSCs) in the adult mouse subventricular zone (SVZ) express the histone methyltransferase EZH2....
ORGANISM(S): Mus musculus 
2014-05-02 | E-GEOD-56394 | biostudies-arrayexpress
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