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ProteomicsVAMP7 KO and ATG5 KO in axonal growth
VAMP7 is involved in autophagy and in exocytosis mediating neurite growth, two yet unconnected cellular pathways. Here we found that nutrient restriction and activation of autophagy stimulated axonal growth while inhibition led to multiple axons. VAMP7 KO neuronal cells showed impaired whereas ATG5 ...
ORGANISM(S): Rattus norvegicus (Rat) 
2021-03-29 | PXD020502 | Pride
Secretion Neurons Vamp7 Amphisomes Axonal growth 
GenomicsMicroarray data of Atg5 WT and KO hematopoietic stem/progenitor cells
Microarray data of Atg5 WT and KO hematopoietic stem/progenitor cells
PRJNA643439 | ENA
TranscriptomicsMicroarray data of Atg5 WT and KO hematopoietic stem/progenitor cells
To comprehensively examine differences of gene expression patterns between WT and ATG5 KO HSCs/progenitors, we isolated LSK cells and conducted the microarray analysis.
ORGANISM(S): Mus musculus 
2021-01-20 | GSE153613 | GEO
TranscriptomicsWild type and ATG5-KO mouse dendritic cells exposed to interleukin-4 (IL4) and/or lipopolisaccharyde (LPS)
Male C57BL/6 normal and ATG5-KO mouse dendritic cells exposed to interleukin-4 (IL4) and/or lipopolisaccharyde (LPS) 24 samples representing the different biological combinations between wild type and ko cells exposed to IL4 and LPS (three replicates for each)
ORGANISM(S): Mus musculus 
2015-06-16 | E-GEOD-56929 | biostudies-arrayexpress
TranscriptomicsWild type and ATG5-KO mouse dendritic cells exposed to interleukin-4 (IL4) and/or lipopolisaccharyde (LPS)
Male C57BL/6 normal and ATG5-KO mouse dendritic cells exposed to interleukin-4 (IL4) and/or lipopolisaccharyde (LPS)
ORGANISM(S): Mus musculus 
2015-06-16 | GSE56929 | GEO
TranscriptomicsNational University of Singapore MEF
miRNA expression of 6h EBSS treatment induced autophagy in Atg5 WT and KO mouse embryonic fibroblasts (MEF) were examined. For the 1st comparison, the control group is Atg5 WT MEF without EBSS treatment, the experiment group is Atg5 KO MEF without EBSS treatment; For the 2nd comparison, the control ...
ORGANISM(S): Mus musculus 
2011-11-21 | E-MTAB-880 | biostudies-arrayexpress
UnknownAtg5 knockout induces alternative autophagy via the downregulation of Akt expression.
Not available
S-EPMC10541375 | biostudies-literature
UnknownDynamic involvement of ATG5 in cellular stress responses.
Not available
S-EPMC4649523 | biostudies-literature
ProteomicsGlobal proteome of Atg5flox:CAG-CreTmx WT and KO neurons
The experiment was performed to identify autophagy targets in wildtype and autophagy-deficient primary neurons. Therefore, cortico-hippocampal neurons were isolated from Atg5flox:CAG-CreTmx mice and treated with Tamoxifen (Tmx) to induce the knockout (KO) or EtOH for wildtype (WT) in-vitro. WT and K...
ORGANISM(S): Mus musculus (Mouse) 
2022-11-15 | PXD031487 | Pride
Atg5 ko Neurons Autophagy 
UnknownBortezomib abrogates temozolomide-induced autophagic flux through an ATG5 dependent pathway.
Not available
S-EPMC9814514 | biostudies-literature
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