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TranscriptomicssiRNA-mediated knockdown of VAMP7 in NTERA2/D1 cells
To unravel the function of VAMP7 in the male sexual differentiation, we carried out in vitro studies of VAMP7 knockdown using siRNA, in the human embryonal carcinoma NTERA2/D1 cells. We knocked down VAMP7 expression in the testicular teratocarcinoma cell line, NTERA2/D1. By comparing the knockdown c...
ORGANISM(S): Homo sapiens 
2014-06-01 | E-GEOD-56102 | biostudies-arrayexpress
ProteomicsVAMP7 KO and ATG5 KO in axonal growth
VAMP7 is involved in autophagy and in exocytosis mediating neurite growth, two yet unconnected cellular pathways. Here we found that nutrient restriction and activation of autophagy stimulated axonal growth while inhibition led to multiple axons. VAMP7 KO neuronal cells showed impaired whereas ATG5 ...
ORGANISM(S): Rattus norvegicus (Rat) 
2021-03-29 | PXD020502 | Pride
Secretion Neurons Vamp7 Amphisomes Axonal growth 
GenomicsRNA-seq of MC903 model with basophils VAMP7 knockout mouse
RNA-seq of MC903 model with basophils VAMP7 knockout mouse
PRJNA1027768 | ENA
GenomicsRNA-seq of MC903-OVA model with basophils VAMP7 knockout mouse
RNA-seq of MC903-OVA model with basophils VAMP7 knockout mouse
PRJNA1021977 | ENA
TranscriptomicssiRNA-mediated knockdown of VAMP7 in NTERA2/D1 cells
To unravel the function of VAMP7 in the male sexual differentiation, we carried out in vitro studies of VAMP7 knockdown using siRNA, in the human embryonal carcinoma NTERA2/D1 cells.
ORGANISM(S): Homo sapiens 
2014-06-01 | GSE56102 | GEO
ProteomicsRole of Late Endosomal Autophagy-Dependent Secretion in Regulating ER and Mitochondrial Stress and Stress Communication
Late endosomal secretion is an unconventional mechanism that relies on VAMP7 and is upregulated in autophagy-null cells. Transcriptomic analysis of VAMP7 knockout (KO) cells revealed significant changes in the expression of genes related to the mitochondria and endoplasmic reticulum (ER) stress. We ...
ORGANISM(S): Rattus norvegicus (Rat) 
2026-01-26 | PXD057152 | Pride
Mitochondrail stress Autophagy Vamp7 
UnknownThe binding of Varp to VAMP7 traps VAMP7 in a closed, fusogenically inactive conformation.
Not available
S-EPMC3605791 | biostudies-literature
GenomicsVAMP7-dependent late endosomal secretion of ER and mitochondrial proteins impacts the tumor microenvironment and macrophage engagement
VAMP7-dependent late endosomal secretion of ER and mitochondrial proteins impacts the tumor microenvironment and macrophage engagement
PRJNA1177365 | ENA
TranscriptomicsRNA-seq of MC903 model with basophils VAMP7 knockout mouse
Differential gene expression of basophil VAMP7 knockout in MC903 induced acute pruritus model
ORGANISM(S): Mus musculus 
2023-11-08 | GSE245289 | GEO
TranscriptomicsVAMP7-dependent late endosomal secretion of ER and mitochondrial proteins impacts the tumor microenvironment and macrophage engagement
Late endosomal secretion is an unconventional secretion mechanism that depends on the SNARE protein VAMP7. We previously showed that VAMP7 mediates the secretion of the ER protein Reticulon3. However, the functional relevance and molecular mechanism of this secretory pathway remain unclear. Here, we...
ORGANISM(S): Rattus norvegicus 
2026-01-26 | GSE280209 | GEO
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