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MetabolomicsMetabolomic profiling of primary mouse proximal tubule cells (mPTCs) derived from 24-week-old CTR and Atg7 PT-KO kidneys
To explore the role of ATG7 in the kidney PT, we crossed mice homozygous for floxed alleles of Atg7 with Ggt1-Cre mice expressing Cre recombinase under the rat Ggt1 (gamma-glutamyltransferase 1) gene promoter. This generated Atg7fl/fl; γGt1cre/cre mice (hereafter referred to as Atg7 PT-KO), in which...
2026-09-30 | MTBLS15857 | MetaboLights
ProteomicsATG7KO SILAC Secretome_Proteome
human lung fibroblasts WT and ATG7KO (two clones) were used for unbiased SILAC/AHA-based secretome and proteome measurements.
ORGANISM(S): Homo sapiens (Human) 
2021-09-10 | PXD025001 | Pride
Autophagy Atg7ko Silac Lung fibroblasts wi26 
UnknownDeficiency of Microglial Autophagy Increases the Density of Oligodendrocytes and Susceptibility to Severe Forms of Seizures.
Not available
S-EPMC7890520 | biostudies-literature
UnknownAutophagy-related 7 (ATG7) regulates food intake and liver health during asparaginase exposure.
Not available
S-EPMC11850126 | biostudies-literature
ProteomicsSecretome profiling of Atg7 KO or Atg14 KO microglia
Analyzing and comparing proteome profiling between WT and Atg7KO or Atg14 KO microglia secreted proteins.
ORGANISM(S): Mus <mouse, Genus> (ncbitaxon:10088) 
2023-04-17 | MSV000091729 | MassIVE
UnknownReceptor-mediated clustering of FIP200 bypasses the role of LC3 lipidation in autophagy.
Not available
S-EPMC7737610 | biostudies-literature
ProteomicsCTLH E3 Ligase Regulates the Degradation of HMG-CoA Synthase 1 Through the Pro/N-end Rule Pathway
Supporting raw MS data for paper (doi: 10.1016/j.molcel.2024.04.026) by Yi S.A. et al, titled "CTLH E3 Ligase Regulates the Degradation of HMG-CoA Synthase 1 Through the Pro/N-end Rule Pathway". Index of RAW files uploaded: - Related to Supplementary Table 1 (HA-9-81-X | WT (1), ATG7KO (2), RB1CC1 ...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2022-11-29 | MSV000090814 | MassIVE
TranscriptomicsAutophagy regulates glucagon secretion via the beta2-adrenergic pathway
Appropriate glucagon secretion from pancreatic alpha cells in response to hypoglycemia is an important component of maintaining glucose homeostasis. Dysregulated glucagon secretion leads to the delayed recovery from a hypoglycemic attack in type 1 diabetes patients which can be lethal. Although eluc...
ORGANISM(S): Homo sapiens 
2024-03-31 | GSE171352 | GEO
GenomicsTranscriptomic profiling of human HAP1 cells before and after nutrient deprivation
Transcriptomic profiling of human HAP1 cells before and after nutrient deprivation
PRJNA420747 | ENA
ProteomicsReceptor-mediated clustering of FIP200 bypasses the role of LC3 lipidation in autophagy
Autophagosome formation requires multiple autophagy-related (ATG) factors. However, we find that a subset of autophagy substrates remains robustly targeted to the lysosome in the absence of several core ATGs, including the LC3 lipidation machinery. To address this unexpected result, we performed gen...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
MSV000086106 | MassIVE
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