Atrogin-1 - OmicsDI

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Unknown (293)
Transcriptomics (23)
Genomics (11)
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Metabolomics (1)

Organisms

Mus musculus (13)
Rattus norvegicus (5)
Homo sapiens (5)
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Mycobacterium tuberculosis SP7 (2)
Mycobacterium tuberculosis SP10 (2)
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Mycobacterium tuberculosis SP22 (2)
Chlamydomonas reinhardtii (2)
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Oncorhynchus tshawytscha (2)
Pseudomonas canadensis (2)
Pseudomonas aeruginosa PAO1H2O (2)
Human alphaherpesvirus 1 strain 17 (2)
Mycobacterium tuberculosis SP1 (2)
Marchantia polymorpha subsp. ruderalis (2)
Methylocystis sp. (2)
Exiguobacterium sp. SH31 (2)
Palaemonetes sp. common grass shrimp associated circular virus (2)
Amaranthus tricolor (2)
Spirochaeta sp. ELBA (2)
Clavibacter nebraskensis NCPPB 2581 (2)
Porites pukoensis (2)
Porphyromonas gingivalis (2)
Leishmania tarentolae (2)
Porphyromonas gingivalis W83 (2)
Human betaherpesvirus 5 (2)
Bothrops insularis (2)
Bothrops jararaca (2)
Danio rerio (1)

Organisms

Mus musculus (5)
Danio rerio (1)
Rattus norvegicus (1)
Homo sapiens (1)

Repository

biostudies-arrayexpress (15)
ENA (11)
geo (8)
iProX (3)
MassIVE (2)
pride (2)
jPOST (1)
MetaboLights (1)

Tissue

Trunk (1)
Muscle (1)

Disease

Normal (1)

Technology Type

Mass Spectrometry (2)
Mass spectrometry assay (1)
Data-independent acquisition (1)
Shotgun proteomics (1)

Instrument Platform

Illumina MiniSeq (1)
Illumina HiSeq 4000 (1)
Q Exactive (1)
Q Exactive Plus (1)
Liquid Chromatography MS - negative - hilic (1)
Liquid Chromatography MS - positive - hilic (1)

Publication Date

2024 (4)
2011 (4)
2007 (3)
2026 (3)
2025 (3)
2012 (2)
2010 (2)
2009 (2)
2017 (2)
2022 (1)
2021 (1)
2014 (1)
2015 (1)

Metabolite Name

(-)-Epothilone E (1)
(-)-Hydroxydihydrobovolide (1)
(-)-Isobebeerine (1)
(-)-trans-C75 (1)
(+)-(E,E)-3-Hydroxy-7-phenyl-4,6-heptadienic acid (1)
(+)-Neomethynolide (1)
(+)-Rauflorine (1)
(+/-)-lefetamine (1)
(¡À)-Camphoric acid (1)
(1R,4R)-p-Mentha-2,8-dien-1-ol (1)
(1S,2R,5S,6R)-5,6-dihydroxy-2-methylcyclohex-3-enecarboxylic acid|massarigenin E (1)
(1S,4S)-4-Hydroxy-3-oxocyclohexane-1-carboxylate (1)
(2S)-2r,8c,17t-triisobutyl-5c,11c,14t-triisopropyl-7-methyl-1,4,10-trioxa-7,13,16-triaza-cyclooctadecane-3,6,9,12,15,18-hexaone|cyclo-(L-2-hydroxy-3-methyl-butyryl->N-methyl-L-leucyl->L-2-hydroxy-3-methyl-butyryl->D-valyl->D-leucyl->L-2-hydroxy-4-methyl-pentanoyl)|Pimaydolid|pimaydolide (1)
(2S)-methylbutanenitrile (1)
(2S,3S,4R,5R)-2,5-epoxy-3,4-dimethyl-8,9-methylenedioxy-10-methoxy-6,11-benzocycloheptan-1-one|gymnothedelignan A (1)
(3E,5Z)-1,3,5-Heptatriene (1)
(5R,6E)-5-Hydroxy-1,7-Diphenyl-6-Hepten-3-One (1)
(6S,8S)-5,6,7,8-tetrahydro-1,3,6-trihydroxy-6-acetyl-8-methylnaphthalene-4-carboxylic acid|ficuselastic acid (1)
(E)-Lyratic acid (1)
(E,E,E)-1,7-diphenyl-1,3,5-heptatriene|1,7-diphenylhepta-1,3,5-triene (1)
(plusmn)12,13-DiHOME (1)
(S)-alpha-Phellandrene (1)
(Z)-2-Methyl-2-buttersaeure-(2-hydroperoxy-2-methyl-3-butenyl)ester (1)
[(1R)-1-(hydroxymethyl)-2-phosphonooxy-ethyl] (5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraenoate (1)
[(2R,5R)-5-(2-Amino-6-oxo-1H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl dihydrogen phosphate (1)
1-(4-oxo-4h-chromen-3-yl)-2,3,4,9-tetrahydro-1h-beta-carboline-3-carboxylic acid (1)
1,1,5-trimethyl-1,2-dihydronaphthalene (1)
1,1-Diphenylurea (1)
1,1'-OXYBIS(4-ISOCYANATOBENZENE) (1)
1,2,4-trithiolane 4-oxide (1)

First Public Date

2026 (2)
2025 (2)
2024 (2)
2014 (2)
2019 (1)
2017 (1)
2015 (1)

Study type

Transcription profiling by array (13)
RNA-seq of coding RNA (2)

Release Date

2025 (37)
2022 (35)
2021 (26)
2023 (26)
2019 (21)
2020 (20)
2017 (18)
2024 (16)
2016 (15)
2018 (14)
2015 (13)
2011 (11)
2013 (11)
2014 (8)
2012 (8)
2010 (8)
2009 (7)
2007 (6)
2026 (5)
2008 (1)
2005 (1)
2004 (1)

Lab affiliation

Department of Neurology, Faculty of Medicine, University of Cologne and University Hospital Cologne, Kerpener Strasse 62, 50937 Cologne, Germany (1)
Australian Regenerative Medicine Institute, Monash University, Wellington Road, Clayton, VIC 3800, Australia (1)

Tags

xref:PubMed:41383117 (1)
xref:PubMed:26464423 (1)
xref:PubMed:30408466 (1)
xref:PubMed:20921137 (1)
xref:PubMed:41511973 (1)
xref:PubMed:23335977 (1)

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Expression data from Ad-atrogin-1-GFP or Ad-GFP infected cardiomyocytes

Cardiomyocyte cell death and renewal are the pivotal events in the pathogenesis of heart failure .Atrogin-1/MAFbx is an ubiquitin E3 ligase that regulates myocardial structure and function through the cellular mechanism of protein degradation. We used DNA microarrays to detail the global trends in g...

ORGANISM(S): Rattus norvegicus

2011-08-02 | E-GEOD-31117 | biostudies-arrayexpress

Atrogin-1 regulates BiP levels - novel therapeutic targets for Duchenne Muscular Dystrophy

Skeletal muscle wasting results from numerous pathological conditions impacting both the musculoskeletal and nervous systems. A unifying feature of these pathologies is the upregulation of members of the E3 ubiquitin ligase family, resulting in increased proteolytic degradation of target proteins. ...

ORGANISM(S): Danio rerio (Zebrafish) (Brachydanio rerio)

2024-03-07 | PXD038406 | Pride