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ProteomicsA safe alternative to H37Rv: the attenuated double auxotroph Mycobacterium tuberculosis ΔleuDΔpanCD
Currently available model organisms such as Mycobacterium smegmatis and Mycobacterium bovis Bacillus Calmette-Guérin (BCG) have significantly contributed to our understanding of tuberculosis (TB) biology, these models have limitations such as differences in genome size, growth rates and virulence. A...
ORGANISM(S): Mycobacterium tuberculosis 
2019-07-30 | PXD013677 | Pride
Biosafety level 2 Model organism Mycobacterium tuberculosis Attenuated auxotroph 
UnknownA uracil auxotroph Toxoplasma gondii exerting immunomodulation to inhibit breast cancer growth and metastasis.
Not available
S-EPMC8665513 | biostudies-literature
UnknownComprehensive Characterization of the Attenuated Double Auxotroph <i>Mycobacterium tuberculosis</i>Δ<i>leuD</i>Δ<i>panCD</i> as an Alternative to H37Rv.
Not available
S-EPMC6710366 | biostudies-literature
UnknownExtended safety and efficacy studies of a live attenuated double leucine and pantothenate auxotroph of Mycobacterium tuberculosis as a vaccine candidate.
Not available
S-EPMC3146342 | biostudies-literature
GenomicsA safe alternative to H37Rv
Comprehensive characterisation of the attenuated double auxotroph Mycobacterium tuberculosis ΔleuDΔpanCD as an alternative to H37Rv
PRJEB32340 | ENA
UnknownBalancing Trained Immunity with Persistent Immune Activation and the Risk of Simian Immunodeficiency Virus Infection in Infant Macaques Vaccinated with Attenuated Mycobacterium tuberculosis or Mycobacterium bovis BCG Vaccine.
Not available
S-EPMC5216431 | biostudies-literature
UnknownNonreplicating, cyst-defective type II Toxoplasma gondii vaccine strains stimulate protective immunity against acute and chronic infection.
Not available
S-EPMC4399033 | biostudies-literature
UnknownA D-Alanine auxotrophic live vaccine is effective against lethal infection caused by Staphylococcus aureus.
Not available
S-EPMC5955480 | biostudies-literature
UnknownErwinia amylovora Auxotrophic Mutant Exometabolomics and Virulence on Apples.
Not available
S-EPMC6643235 | biostudies-literature
UnknownA New Live Auxotrophic Vaccine Induces Cross-Protection against Klebsiella pneumoniae Infections in Mice.
Not available
S-EPMC9227041 | biostudies-literature
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