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MetabolomicsExtreme genome diversity and cryptic speciation in a harmful algal bloom forming eukaryote

Harmful algal blooms (HABs) of the toxic haptophyte Prymnesium parvum are a recurrent problem in many inland and estuarine waters around the world. Strains of P. parvum vary in the toxins they produce and in other physiological traits associated with HABs, but the genetic basis ...

2023-04-26 | MTBLS5893 | MetaboLights
MetabolomicsGNPS - MITOMICS: defining mitochondrial protein functions through deep multi-omic profiling
Mitochondria are epicenters of eukaryotic metabolism and bioenergetics. Pioneering efforts in recent decades have established the core protein componentry of these organelles and have linked their dysfunction to over 150 distinct disorders. However, hundreds of mitochondrial proteins still lack clea...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2021-01-11 | MSV000086685 | GNPS
UnknownVisual Semantic Encoding and Identification of Naturalistic Movies via High-Density Diffuse Optical Tomography.
Not available
S-EPMC12713126 | biostudies-literature
GenomicsBAF155 methylation at R1064 creates unique chromatin association patterns
CARM1, a coactivator for various cancer-relevant transcription factors, is overexpressed in breast cancer. To elucidate the functions of CARM1 in tumorigenesis, we knocked out CARM1 from several breast cancer cell lines using Zinc-Finger Nuclease technology, which resulted in drastic phenotypic and ...
ORGANISM(S): Homo sapiens 
2014-03-28 | E-GEOD-52964 | biostudies-arrayexpress
TranscriptomicsGlobal effects of the small RNA biogenesis machinery on the Arabidopsis thaliana transcriptome
In Arabidopsis thaliana, four different DICER-LIKE (DCL) proteins have distinct, but partially overlapping functions in the biogenesis of microRNAs (miRNAs) and small interfering RNAs (siRNAs) from longer, non-coding precursor RNAs. To analyze the impact of different components of the small RNA (...
ORGANISM(S): Arabidopsis thaliana 
2010-05-07 | E-GEOD-21685 | biostudies-arrayexpress
UnknownSurface boulder banding indicates Martian debris-covered glaciers formed over multiple glaciations.
Not available
S-EPMC7848752 | biostudies-literature
TranscriptomicsJuvenile obesity in Ossabaw swine produces artery-specific transcriptional changes
We adopted a transcriptome-wide microarray analysis approach to determine the extent to which vascular gene expression is altered as a result of juvenile obesity and identify obesity-responsive mRNAs. We examined transcriptional profiles in the left anterior descending coronary artery (LAD), perivas...
ORGANISM(S): Sus scrofa 
2013-05-29 | E-GEOD-41636 | biostudies-arrayexpress
UnknownAssociation of insulin resistance, from mid-life to late-life, with aortic stiffness in late-life: the Atherosclerosis Risk in Communities Study.
Not available
S-EPMC6986071 | biostudies-literature
TranscriptomicsImpact of exercise training on endothelial transcriptional profiles in healthy swine: A genome-wide microarray analysis
While the salutary effects of exercise training on conduit artery endothelial cells have been reported in animals and humans with cardiovascular risk factors or disease, whether a healthy endothelium is alterable with exercise training is less certain. The purpose of this study was to evaluate the ...
ORGANISM(S): Sus scrofa 
2011-12-02 | E-GEOD-26663 | biostudies-arrayexpress
GenomicsThe RUNX2 Cistrome in Osteoblasts: Characterization, Downregulation Following Differentiation and Relationship to Gene Expression [ChIP-Seq]
RUNX2 is a transcription factor that is first expressed in early osteoblast-lineage cells and represents a primary determinant of osteoblastogenesis. While numerous target genes are regulated by RUNX2, little is known of sites on the genome occupied by RUNX2 or of the gene networks that are control...
ORGANISM(S): Mus musculus 
2014-04-24 | E-GEOD-41920 | biostudies-arrayexpress
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