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TranscriptomicsTranscriptional profiling of Rattus norvegicus brain hippocampal CA1 regions after kainic acid induced status epilepticus and untreated controls.
In this study we used microarray analysis to reveal the gene expression profile of the hippocampal CA1 subregion, which was laser-capture microdissected one week after kainic acid (KA)-induced status epilepticus (SE) in postnatal day 21 (P21) rats. These rats are developmentally roughly comparable t...
ORGANISM(S): Rattus norvegicus 
2010-10-25 | E-TABM-881 | biostudies-arrayexpress
ProteomicsAutoantibody Epitope Spreading in the Pre-Clinical Phase Predicts Progression to Rheumatoid Arthritis [ANALYTE: ANTIGEN]
Rheumatoid arthritis is a prototypical autoimmune arthritis affecting nearly 1% of the world population and is a significant cause of worldwide disability. Though prior studies have demonstrated the appearance of RA-related autoantibodies years before the onset of clinical RA, the pattern of immunol...
ORGANISM(S): Homo sapiens 
2011-09-09 | E-GEOD-32016 | biostudies-arrayexpress
ProteomicsAutoantibody Epitope Spreading in the Pre-Clinical Phase Predicts Progression to Rheumatoid Arthritis [ANALYTE: Cytokine or chemokine]
Rheumatoid arthritis is a prototypical autoimmune arthritis affecting nearly 1% of the world population and is a significant cause of worldwide disability. Though prior studies have demonstrated the appearance of RA-related autoantibodies years before the onset of clinical RA, the pattern of immunol...
ORGANISM(S): Homo sapiens 
2011-09-09 | E-GEOD-32019 | biostudies-arrayexpress
TranscriptomicsSerum Inflammatory Mediators as Markers of Human Lyme Disease Activity
Chemokines and cytokines are key signaling molecules that orchestrate the trafficking of immune cells, direct them to sites of tissue injury and inflammation and modulate their states of activation and effector cell function. We have measured, using a multiplex-based approach, the levels of 58 immun...
ORGANISM(S): Homo sapiens 
2014-04-25 | E-GEOD-55815 | biostudies-arrayexpress
UnknownAssociation of post-operative ctDNA detection with outcomes of patients with early breast cancers.
Not available
S-EPMC11402396 | biostudies-literature
TranscriptomicsExpression analysis of Streptococcus pyogenes MGAS315 induced with XIP pheromone
Whole genome expression profile comparing MGAS315 treated with XIP pheromone versus vehicle-treated cells Interpretations are described further in the manuscript to be submitted: authors Mashburn-Warren, Morrison, and Federle. Title: The Cryptic Competence Pathway in Streptococcus pyogenes is Contro...
ORGANISM(S): Streptococcus pyogenes MGAS315 
2012-05-31 | E-GEOD-37974 | biostudies-arrayexpress
TranscriptomicsEccentric exercise activates novel transcriptional regulation of hypertrophic signaling pathways
Full title: Eccentric exercise activates novel transcriptional regulation of hypertrophic signaling pathways not affected by hormone changes. Unaccustomed eccentric exercise damages muscle tissue stimulating mechanisms of recovery and remodeling that may be affected by cellular protection by the sex...
ORGANISM(S): Homo sapiens 
2009-12-16 | E-GEOD-19062 | biostudies-arrayexpress
TranscriptomicsDetermination of prognosis in metastatic melanoma through integration of clinico-pathologic, mutation, mRNA, microRNA, and protein information
In patients with metastatic melanoma, the identification and validation of accurate prognostic biomarkers will assist rational treatment planning. Studies based on "-omics" technologies have focussed on a single high-throughput data type such as gene or microRNA transcripts. Occasionally, ...
ORGANISM(S): Homo sapiens 
2014-08-18 | E-GEOD-54467 | biostudies-arrayexpress
TranscriptomicsMacrophage gene expression associated with remodeling of the prepartum rat cervix: Microarray and pathway analyses
As the critical gatekeeper for birth, prepartum remodeling of the cervix is associated with increased resident macrophages (MM-OM-^F), proinflammatory processes, and extracellular matrix degradation. This study tested the hypothesis that expression of genes unique to MM-OM-^Fs characterizes the prep...
ORGANISM(S): Rattus norvegicus 
2015-01-27 | E-GEOD-65265 | biostudies-arrayexpress
TranscriptomicsA novel recurrent mutation in MITF predisposes to familial and sporadic melanoma
We identified a novel germline mutation of the microphthalmia-associated transcription factor (MITF - E318K). This mutation was found to be present in numerous melanoma families, as well as the general population, where its association with melanoma has a significant effect. We determined the effe...
ORGANISM(S): Homo sapiens 
2011-12-01 | E-GEOD-31269 | biostudies-arrayexpress
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