Autism spectrum disorder

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Organisms

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Aerococcus urinae NBRC 15544 = CCUG 36881 (63)
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mouse gut metagenome (3)
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gut metagenome (1)
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unidentified (1)

Repository

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geo (396)
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Tissue

Brain (38)
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Blood (2)
Blood cell (2)
Blood serum (2)
CNS neuron (sensu Vertebrata) (2)
Electrically active cell (2)
Pluripotent stem cell (2)
Blood (1)
Basis pedunculi cerebri (1)
Blood plasma (1)
Cerebral cortex (1)
Cerebral cortex neuron (1)
Cervix epithelium (1)
Early embryonic cell (1)
Embryonic stem cell (1)
Endothelium (1)
Head (1)
Hippocampus (1)
Interstitial cell of pineal gland (1)
Keratinocyte (1)
Kidney (1)
Microglial cell (1)
Neural progenitor cell (1)
Neural tissue (1)
Neuron of cerebral cortex (1)
Permanent cell line cell (1)
Pineal gland (1)

Disease

Autism spectrum disorder (28)
Autistic disorder (3)
Fragile X syndrome (2)
Inflammatory Bowel Diseases (1)
Autism (1)
Autism Spectrum Disorder (1)
Typical development (1)
Attention deficit hyperactivity disorder (1)
Disease free (1)
Epilepsy (1)
Neurodevelopmental abnormality (1)
Prostate cancer (1)
Residual chronic schizophrenia (1)
Rett syndrome (1)

Technology Type

Mass Spectrometry (64)
Shotgun proteomics (28)
Bottom-up proteomics (15)
Illumina HiSeq 2000 (8)
Affinity purification coupled with mass spectrometry proteomics (8)
Data-dependent acquisition (7)
Mass spectrometry assay (6)
Mass spectrometry (6)
Data-independent acquisition (5)
SWATH MS (4)
Top-down proteomics (2)
Illumina HiSeq 2000, ILLUMINA (1)
NMR spectroscopy (1)
ESI (1)
All-ion fragmentation (1)
Chemical cross-linking coupled with mass spectrometry proteomics (1)
Gel-based experiment (1)
HDMSE (1)
SRM/MRM (1)

Instrument Platform

Illumina NovaSeq 6000 (13)
Illumina HiSeq 2500 (10)
- (4)
Orbitrap Fusion Lumos (4)
Liquid Chromatography MS - positive - reverse-phase (4)
Liquid Chromatography MS - positive - reverse phase (4)
IEO HPC (3)
TripleTOF 5600+ (3)
Orbitrap Exploris 480 (3)
Orbitrap Fusion (3)
Q Exactive HF (3)
Liquid Chromatography MS - negative - reverse phase (3)
None (2)
NextSeq 500 (2)
Illumina HiSeq 2000 (2)
Q Exactive HF-X (2)
Q Exactive Plus (2)
Capillary electrophoresis MS - negative - normal-phase-chromatography (2)
Nanodrop (1)
Omni ATAC kit (1)
Cutadapt, STAR (1)
TruSeq Stranded mRNA Sample Prep Kit (Illumina) (1)
BD InFlux Cytometer (Becton-Dickinson) (1)
NA (1)
R (1)
DNBSEQ-G400 (1)
Illumina MiSeq (1)
Illumina HiSeq 4000 (1)
Affymetrix (1)
TripleTOF 5600 (1)

Publication Date

2026 (96)
2025 (78)
2023 (57)
2022 (50)
2024 (48)
2020 (38)
2014 (38)
2021 (38)
2019 (33)
2018 (30)
2016 (28)
2013 (28)
2015 (26)
2012 (26)
2011 (24)
2017 (23)
2010 (10)
2008 (9)
2007 (7)
2009 (1)

CHEBI ID

CHEBI:17626 (3)
CHEBI:17553 (3)
CHEBI:48430 (3)
CHEBI:17202 (3)
CHEBI:16695 (3)
CHEBI:17802 (3)
CHEBI:16708 (3)
CHEBI:14336 (3)
CHEBI:15741 (3)
CHEBI:17268 (3)
CHEBI:17154 (3)
CHEBI:16865 (3)
CHEBI:16196 (3)
CHEBI:16235 (3)
CHEBI:17203 (3)
CHEBI:15891 (3)
CHEBI:18300 (3)
CHEBI:18050 (3)
CHEBI:15843 (3)
CHEBI:17385 (3)
CHEBI:16704 (3)
CHEBI:16015 (3)
CHEBI:16027 (3)
CHEBI:16761 (3)
CHEBI:30915 (3)
CHEBI:16919 (3)
CHEBI:17191 (3)
CHEBI:15603 (3)
CHEBI:17895 (3)
CHEBI:17295 (3)

Metabolite Name

Acetyl-CoA (2)
NADPH (2)
Trehalose 6-phosphoric acid (1)
3-phosphoglycerol (1)
Erythose-4-phosphoric acid (1)
Ribulose-1,5-bisphosphate (1)
ADPglucose (1)
Nicotinamide adenine dinucleotide phosphate (NADP+) (1)
Beta-Nicotinamide adenine dinucleotide reduced (NADH) (1)
Beta-Nicotinamide adenine dinucleotide (NAD+) (1)
Adenosine 5'-triphosphate (5'-ATP) (1)
Inosine 5'-monophosphate (5'-IMP) (1)
Ketoleucine (4-Methyl-2-oxopentanoic acid) (1)
S-(5'-Adenosyl)-L-methionine (SAM) (1)
Adenosine 5'-monophosphate (5'-AMP) (1)
Pentanedioic acid (1)
Palatinose (1)
Oleanitrile (1)
Methylsuccinic acid (1)
Methyl linolelaidate (1)
Methyl 16-octadecenoate (1)
Inositol phosphate (1)
Glucosyl glycerol (1)
Dehydroalanine (possibly from cysteine) (1)
Cyclohexaneacetic acid (1)
Cholestan-3-ol (1)
Cholest-7-en-3-ol (1)
Beta-cyano-L-alanine (1)
3-methylpiperazine-2,5-dione (1)
3-deoxyhexonic acid (1)

First Public Date

2026 (100)
2025 (92)
2023 (61)
2024 (55)
2021 (53)
2020 (48)
2022 (42)
2019 (38)
2018 (27)
2014 (25)
2017 (21)
2016 (12)
2015 (11)
2013 (8)

Classification

bacteria (1)

Study status

Terminated (1)

Study type

Transcription profiling by array (83)
RNA-seq of coding RNA (40)
Comparative genomic hybridization by array (18)
Methylation profiling by array (10)
ChIP-seq (8)
RNA-seq of coding RNA from single cells (5)
Methylation profiling by high throughput sequencing (5)
DNA-seq (3)
ChIP-chip by tiling array (2)
Other (2)
Transcription profiling by SAGE (1)
Human - Two-color microarray (1)
Human - Single-cell sequencing (1)
Transcription profiling by tiling array (1)
Capture-C (1)
ATAC-seq (1)
ScATAC-seq (1)
RNA-seq of total RNA (1)
RNA-seq of non coding RNA (1)
Observational (1)

Release Date

2022 (1041)
2021 (946)
2025 (918)
2023 (859)
2020 (752)
2024 (724)
2019 (584)
2018 (527)
2017 (409)
2016 (285)
2015 (243)
2014 (214)
2013 (119)
2026 (111)
2012 (86)
2011 (60)
2010 (46)
2008 (22)
2009 (17)
2007 (12)
2005 (4)
2006 (3)
2003 (2)
2004 (1)
2001 (1)

Lab affiliation

Key Laboratory of Brain Functional Genomics of Shanghai and Ministry of Education, Institute of Brain Functional Genomics, School of Life Science and the Collaborative Innovation Center for Brain Science, East China Normal University, Shanghai, China (3)
Institute of Genetics & Developmental Biology, Chinese Academy of Sciences (2)
University Health Network, Krembil Research Institute (2)
Bernstein Professor Emeritus in Adult Psychiatry Department of Psychiatry and Behavioral Sciences University of Minnesota Medical School (1)
Bernstein Professor Emeritus in Adult Psychiatry Department of Psychiatry and Behavioral Sciences University of Minnesota Medical School Minneapolis, Minnesota, USA (1)
Biomedical Research Institute, Foundation for Research and Technology-Hellas, University Campus, 45110 Ioannina, Greece (1)
Biomolecular characterization unit, Center for Sustainable Resource Science, RIKEN (1)
Department of Anatomy & Neurobiology University of Tennessee Health Science Center (1)
Department of Biochemistry and Biomedical Sciences McMaster University (1)
Department of Biochemistry and Molecular Biology, Cumming School of Medicine, University of Calgary, Calgary, AB, Canada (1)
Department of Biological Sciences, Korea Advanced Institute for Science and Technology (KAIST), Daejeon 34141, Korea (1)
Department of Chemistry & Biomolecular Science Clarkson University, Potsdam, NY, 13699, Box 5810 (1)
Department of Laboratory Medicine and Pathobiology, University of Toronto (1)
Department of Molecular Biology, Faculty of Science, Radboud Institute for Molecular Life Sciences, Radboud University Nijmegen, Nijmegen 6525, the Netherlands. (1)
Department of New Biology, DGIST, Daegu 42988, Republic of Korea (1)
Department of Psychiatry, Seaver Autism Center for Research and Treatment, Mindich Child Health and Development Institute, Friedman Brain Institute, Alper Center for Neural Development and Regeneration, Icahn School of Medicine at Mount Sinai, USA (1)
Department of Public Health and Medical Technology, Xiamen Medical College (1)
Division head B230 Proteomics of Stem Cells and Cancer (1)
Genetic and Molecular Basis of Neurodevelopmental Disorders, IST Austria, Klosterneuburg, Lower Austria, Austria (1)
Genomic Medicine Institute, Cleveland Clinic (1)
Hebrew University of Jerusalem (1)
IRCCS Istituto G Gaslini (1)
Institut Pasteur (1)
Institute for Immunology UMC University of Mainz (1)
Institute for Research in Biomedicine (IRB Barcelona), The Barcelona Institute of Science and Technology, 08028 Barcelona, Spain (1)
Institute of Bioinformatics, International Technology Park, Bangalore 560 066, India (1)
Institute of Medical Sciences, University of Aberdeen, UK (1)
Jösch Group "Neuroethology", ISTA (Institute of Science and Technology Austria), Am Campus 1, Klosterneuburg, Niederösterreich, Austria (1)
Korea Brain Research Institute (1)
Lab Head, UQ Diamantina Institute,The University of Queensland (1)

Location

United States (1)

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Human Gut Microbiota from Autism Spectrum Disorder Promote Behavioral Symptoms in Mice

Autism spectrum disorder (ASD) manifests as alterations in complex human behaviors including social communication and stereotypies. In addition to genetic risks, the gut microbiome differs between typically-developing (TD) and ASD individuals, though it remains unclear whether the microbiome contrib...

2019-07-04 | MTBLS726 | MetaboLights

Gut Microbiota and Urine Metabolomics Signature in Autism Spectrum Disorder children from Southern China

To determine the gut microbiota and urine metabolomics signature and identify the regional characteristics in Autism spectrum disorder (ASD), we conducted a cohort study of 88 well-characterized participants from Guangxi Zhuang Autonomous Region in Southern China. Gut microbiota and urine metabo...

2025-06-16 | MTBLS12605 | MetaboLights

Plasma metabolomic profiling of individuals with autism spectrum disorder and their family members.

Not available

ORGANISM(S): Homo sapiens

ST002332 | MetabolomicsWorkbench

RNA-seq of 36 individuals with autism spectrum disorder

To assess the clinical impact of splice-altering noncoding mutations in autism spectrum disorder (ASD), we used a deep learning framework (SpliceAI) to predict the splice-altering potential of de novo mutations in 3,953 individuals with ASD from the Simons Simplex Collection. To validate these predi...

ORGANISM(S): Homo sapiens

2018-11-25 | E-MTAB-7351 | biostudies-arrayexpress

Acute rapamycin rescues the hyperexcitable phenotype of accumbal medium spiny neurons in the valproic acid rat model of autism spectrum disorder

The aim of the study was to investigate the involvement of the mTOR pathway in the autism spectrum disorder. Adolescent male rats, prenatally exposed to valproic acid (500 mg/kg ip on gestational day 12.5), were treated with the mTOR inhibitor rapamycin (10 mg/kg, ip, two consecutive days starting a...

ORGANISM(S): Rattus norvegicus

2022-09-06 | E-MTAB-12056 | biostudies-arrayexpress

Expression profiling of skin fibroblast, iPSC, iPSC-derived neural progenitors, and iPSC-derived neurons from Autism Spectrum Disorder male patients and their unaffected normal male siblings

Autism spectrum disorder (ASD) is an early onset neurodevelopmental disorder, which is characterized by disturbances of brain function and behavioral deficits in core areas of impaired reciprocal socialization, impairment in communication skills, and repetitive or restrictive interests and behaviors...

ORGANISM(S): Homo sapiens

2016-07-01 | E-GEOD-65106 | biostudies-arrayexpress

Global methylation profiling of lymphoblastoid cell lines reveals epigenetic contributions to autism spectrum disorders

Autism is currently considered a multigene disorder with epigenetic influences. To investigate the contribution of DNA methylation to autism spectrum disorders, we have recently completed large-scale methylation profiling by CpG island microarray analysis of lymphoblastoid cell lines (LCL) derived ...

ORGANISM(S): Homo sapiens

2010-04-27 | E-GEOD-21395 | biostudies-arrayexpress

Investigation of post-transcriptional gene regulatory networks associated with autism spectrum disorders (ASD) by microRNA expression profiling of lymphoblastoid cell lines

Autism spectrum disorders (ASD) are neurodevelopmental disorders characterized by abnormalities in reciprocal social interactions and language development and/or usage, and by restricted interests and repetitive behaviors. Differential gene expression of neurologically relevant genes in lymphoblasto...

ORGANISM(S): Homo sapiens

2010-04-09 | E-GEOD-21086 | biostudies-arrayexpress

Gene expression profiling differentiates autism case-controls and phenotypic variants of autism spectrum disorders

Autism spectrum disorders (ASD) are neurodevelopmental disorders characterized by delayed/abnormal language development, deficits in social interaction, repetitive behaviors and restricted interests. The heterogeneity in clinical presentation of ASD, likely due to different etiologies, complicates ...

ORGANISM(S): Homo sapiens

2010-05-17 | E-GEOD-15402 | biostudies-arrayexpress

Metaproteomics investigation on the gut microbiota of children affected by Autism Spectrum Disorder

Metaproteomics investigation of the Gut Microbiota in young subjects with Autism Spectrum Disorders and their relatives

ORGANISM(S): Bacteria (ncbitaxon:2)

2020-04-06 | MSV000085232 | MassIVE

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