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ProteomicsProteomic analysis of retinal tissue in an S100B autoimmune glaucoma model
Glaucoma is not only the second leading cause of blindness worldwide, but patient numbers will also increase significantly in the coming years due to aging societies. Glaucoma is a progressive optic neuropathy with changes at the optic nerve head, gradual retinal ganglion cell (RGC) death, and visua...
ORGANISM(S): Rattus norvegicus (Rat) 
2022-02-16 | PXD023995 | Pride
Autoimmune glaucoma Proteomics Ls-ms/ms Normal tension S100b 
UnknownIs glaucoma an autoimmune disease?
Not available
S-EPMC7586712 | biostudies-literature
ProteomicsSynthetic polyclonal-derived CDR peptides as innovative strategy in glaucoma therapy
The pathogenesis of glaucoma is strongly associated with the occurrence of autoimmune-mediated loss of retinal ganglion cells (RGCs) and recently it was proven that specific antibody-derived signature peptides are significantly differentially expressed in sera of primary open angle glaucoma patients...
ORGANISM(S): Homo sapiens (Human) Sus scrofa domesticus (domestic pig) 
2019-08-15 | PXD014718 | Pride
Glaucoma  autoimmunity  synthetic cdr peptides  neuroprotection  htra2  sus scrofa domesticus 
GenomicsImmune Tolerance to HSP60 Attenuates Neurodegeneration in Glaucoma
Immune Tolerance to HSP60 Attenuates Neurodegeneration in Glaucoma
PRJNA1119479 | ENA
UnknownTransfer of the Experimental Autoimmune Glaucoma Model from Rats to Mice-New Options to Study Glaucoma Disease.
Not available
S-EPMC6566658 | biostudies-literature
TranscriptomicsImmune Tolerance to HSP60 Attenuates Neurodegeneration in Glaucoma
Our previous study suggests that CD4+ T cells primed by bacterial heat shock proteins (HSP) mediate an autoimmune mechanism contributing to the pathogenesis of glaucoma. The present study showed that the activity of CD4+ T cells from the peripheral blood mononuclear cells (PBMC) of POAG patients was...
ORGANISM(S): Homo sapiens 
2025-06-11 | GSE268936 | GEO
UnknownS100B immunization triggers NFκB and complement activation in an autoimmune glaucoma model.
Not available
S-EPMC6026137 | biostudies-literature
UnknownIn a novel autoimmune and high-pressure glaucoma model a complex immune response is induced.
Not available
S-EPMC10955086 | biostudies-literature
UnknownSimultaneous Complement Response via Lectin Pathway in Retina and Optic Nerve in an Experimental Autoimmune Glaucoma Model.
Not available
S-EPMC4887475 | biostudies-literature
UnknownHeat Shock Protein Upregulation Supplemental to Complex mRNA Alterations in Autoimmune Glaucoma.
Not available
S-EPMC9599116 | biostudies-literature
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