Sort   by:  
 Page size 
Glaucoma is not only the second leading cause of blindness worldwide, but patient numbers will also increase significantly in the coming years due to aging societies. Glaucoma is a progressive optic neuropathy with changes at the optic nerve head, gradual retinal ganglion cell (RGC) death, and visua...
ORGANISM(S): Rattus norvegicus (Rat) 
2022-02-16 | PXD023995 | Pride
The human neuroblastoma cell line Lan5 cells were cultured in complete DMEM till 80% confluence, then placed at 60000 cells per squared cm. Cells were then plated in 24-well plates for cell viability assay and in T75 flasks for RNA isolation. Medium was replaced with serum-free fresh medium for 12 h...
ORGANISM(S): Homo sapiens 
Project aims at characterisation of the structural dynamics of complex partners in isolation and in complex in different composition of metal ions, Ca, Zn, Cu to establish the impact of metal ions and peptide on S100B stuctural features and its oligomerisation status..
ORGANISM(S): Homo sapiens (Human) 
2025-05-07 | PXD057057 | Pride
Suprachiasmatic nucleus regulation of brown fat thermogenesis via ADRB3-S100B axis
A key role for NLRP3 signaling in preterm labor and birth driven by the alarmin S100B
The suprachiasmatic nucleus (SCN), the central circadian pacemaker, orchestrates daily metabolic rhythms, yet its role in substrate selection and thermogenic adaptation remains insufficiently understood. Here, we show that SCN lesioning abolishes the adaptive suppression of brown adipose tissue (BAT...
ORGANISM(S): Mus musculus 
2025-11-06 | GSE300640 | GEO
HDX-MS experiment of the interaction between the full-length RAGE and S100B proteins. HDX results we demonstrate an allosteric coupling of the distal extracellular V-domains and the transmembrane region to hypothesize about the mechanism of signal transmission by RAGE
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2021-01-18 | MSV000086718 | MassIVE
Invasive aspergillosis (IA) is a devastating opportunistic infection and its treatment constitutes a considerable burden for the health care system. Immunocompromised patients are at an increased risk for IA, which is mainly caused by the species Aspergillus fumigatus. An early and reliable diagnosi...
ORGANISM(S): Homo sapiens 
2016-03-31 | GSE78000 | GEO
Invasive aspergillosis (IA) is a devastating opportunistic infection and its treatment constitutes a considerable burden for the health care system. Immunocompromised patients are at an increased risk for IA, which is mainly caused by the species Aspergillus fumigatus. An early and reliable diagnosi...
ORGANISM(S): Homo sapiens 
The human neuroblastoma cell line Lan5 cells were cultured in complete DMEM till 80% confluence, then placed at 60000 cells per squared cm. Cells were then plated in 24-well plates for cell viability assay and in T75 flasks for RNA isolation. Medium was replaced with serum-free fresh medium for 12 h...
ORGANISM(S): Homo sapiens 
2010-05-31 | GSE15218 | GEO
Sort   by:  
 Page size