In eubacteria, decoding of isoleucine codon AUA requires a specialized tRNA (tRNAIle2) modified with lysidine (k²C) at the anticodon wobble position (C34). This modification converts the tRNA’s decoding specificity from methionine (AUG) to isoleucine (AUA). Recently, aminovaleramide cytidine (ava²C)...
ORGANISM(S): Escherichia coli
