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TranscriptomicsCohesin profiling at DSBs
Chromatin undergoes major remodeling around DNA double strand breaks (DSB) to promote repair and DNA damage response (DDR) activation. We recently reported a high resolution map of gammaH2AX around multiple breaks on the human genome, using a new cell-based DSB inducible system. In an attempt to fur...
ORGANISM(S): Homo sapiens 
2012-01-01 | E-TABM-1164 | biostudies-arrayexpress
UnknownA new species of Schlegelia (Schlegeliaceae) from wet montane forest of Colombia and a key for the species of the genus.
Not available
S-EPMC10439459 | biostudies-literature
GenomicsTranscriptionally active chromatin channels DNA double-strand breaks to RAD51-dependent repair
Cells have developed effective mechanisms, namely homologous recombination (HR) and non-homologous end-joining (NHEJ), to repair DNA double-strand breaks (DSBs), which are considered to be the most deleterious type of damage that can challenge genome integrity. While these pathways coexist to repair...
ORGANISM(S): Homo sapiens 
2014-03-23 | E-MTAB-1241 | biostudies-arrayexpress
GenomicsChIP-Seq mapping of histone modifications at multiple DNA Double Strand Breaks
DNA Double Strands Breaks (DSBs) are highly detrimental since they can lead to mutations and chromosomes rearrangements (amplification, deletion, translocation and chromosome loss). Here, we used in a standardized system, where multiples DSBs are induced at defined positions across the human genome ...
ORGANISM(S): Homo sapiens 
2018-09-27 | E-MTAB-5817 | biostudies-arrayexpress
UnknownDesign, synthesis, and structure-activity relationship studies of 6H-benzo[b]indeno[1,2-d]thiophen-6-one derivatives as DYRK1A/CLK1/CLK4/haspin inhibitors.
Not available
S-EPMC11487425 | biostudies-literature
UnknownTranscatheter Occlusion of Coronary-Pulmonary Fistula With a Liquid Embolic Agent After Evaluation by FFR.
Not available
S-EPMC9175142 | biostudies-literature
UnknownMidterm outcomes of minimally invasive mitral valve surgery in a heterogeneous valve pathology cohort: respect or resect?
Not available
S-EPMC10323544 | biostudies-literature
UnknownH2A.Z depletion impairs proliferation and viability but not DNA double-strand breaks repair in human immortalized and tumoral cell lines.
Not available
S-EPMC3956535 | biostudies-literature
UnknownEcological momentary assessment of daily patient-reported outcomes and actigraphy-measured physical activity and sleep in patients with rheumatoid arthritis and spondyloarthritis: a study protocol.
Not available
S-EPMC12911789 | biostudies-literature
UnknownScreen identifies bromodomain protein ZMYND8 in chromatin recognition of transcription-associated DNA damage that promotes homologous recombination.
Not available
S-EPMC4298138 | biostudies-literature
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