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TranscriptomicsGlobal characterization of the oocyte-to-embryo transition in C. elegans uncovers a novel mRNA turnover mechanism
The oocyte-to-embryo transition (OET) is thought to be mainly driven by post-transcriptional gene regulation. However, expression of both RNAs and proteins during the OET has not been comprehensively assayed. Furthermore, specific molecular mechanisms that regulate gene expression during OET are lar...
ORGANISM(S): Caenorhabditis elegans 
2014-07-02 | E-GEOD-58141 | biostudies-arrayexpress
UnknownRisk factors for inflammatory and non-inflammatory breast cancer in North Africa.
Not available
S-EPMC10440960 | biostudies-literature
TranscriptomicsConserved functional antagonism between CELF and MBNL proteins regulates stem cell-specific alternative splicing and regeneration in planarians
Understanding gene regulation in stem cells is key to understanding stem cell biology.Contrary to transcriptional regulation the function of alternative splicing (AS) in stem cells is poorly understood. Here we study function and mechanisms of AS in a powerful in vivo model for stem cell biology, th...
ORGANISM(S): Schmidtea mediterranea 
2016-08-01 | E-GEOD-75296 | biostudies-arrayexpress
TranscriptomicsConserved functional antagonism between CELF and MBNL proteins regulates stem cell-specific alternative splicing and regeneration in planarians
Here, we analyze the RNA-binding preferences of the planarian smed-mbnl-like-2, smed-mbnl-1 (isoform X1), smed-bruli, smed-mbnl-1 (isoform Xins), and smed-mbnl-like-1 protein using RNAcompete. In the RNAcompete assay, a purified GST-tagged protein is incubated with an excess of RNA pool and bound RN...
ORGANISM(S): synthetic construct 
2016-08-01 | E-GEOD-75554 | biostudies-arrayexpress
UnknownMapping artificial intelligence adoption in hepatology practice and research: challenges and opportunities in MENA region.
Not available
S-EPMC12463891 | biostudies-literature
UnknownPancreatic surgery outcomes: multicentre prospective snapshot study in 67 countries.
Not available
S-EPMC10771125 | biostudies-literature
UnknownImpact of opioid-free analgesia on pain severity and patient satisfaction after discharge from surgery: multispecialty, prospective cohort study in 25 countries.
Not available
S-EPMC10783642 | biostudies-literature
UnknownAwareness and preparedness of healthcare workers against the first wave of the COVID-19 pandemic: A cross-sectional survey across 57 countries.
Not available
S-EPMC8694437 | biostudies-literature
UnknownSARS-CoV-2 vaccination modelling for safe surgery to save lives: data from an international prospective cohort study.
Not available
S-EPMC7995808 | biostudies-literature
UnknownTiming of surgery following SARS-CoV-2 infection: an international prospective cohort study.
Not available
S-EPMC8206995 | biostudies-literature
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