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The zebrafish has the capacity to regenerate its heart after severe injury. While the function of a few genes during this process has been studied, we are far from fully understanding how genes interact to coordinate heart regeneration. To enable systematic insights into this phenomenon, we generate...
ORGANISM(S): Danio rerio 
Using basal‐like untransformed cells, MCF10A, as a model system, data from our laboratory showed that both mRNAs and microRNAs exhibit dynamic changes in expression following EGF stimulation (Amit et al, 2007; Avraham et al, 2010; Kostler et al, 2013). We further demonstrated that the inducible mRNA...
ORGANISM(S): Homo sapiens 
The long non coding RNA LIMT was found in our study to inhibit cellular migration in vitro and to inhibit colonization of mammary tumorigenic cells in lungs of mice in vivo. In order to uncover the mechanism enabling these tumor suppressive functions of LIMT the expression of this lncRNA was knocked...
ORGANISM(S): Homo sapiens 
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