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TranscriptomicsEstimates of total imprint number withstand transcriptome test
The number of transcripts where allelic bias is dependent parent-of-origin was predicted at 100-200 until two recent studies applied RNA-Seq to brain regions from reciprocally crossed inbred mouse strains and identified over a thousand novel imprinted loci, including hundreds present in only males o...
ORGANISM(S): Mus musculus 
2011-12-01 | E-GEOD-27016 | biostudies-arrayexpress
TranscriptomicsDigital gene expression and global mapping of polyadenylation sites with PolyA-Seq
We describe PolyA-Seq, a strand-specific method for high-throughput sequencing of the 3' ends of polyadenylated transcripts. PolyA-Seq is as accurate for digital gene expression as existing RNA sequencing approaches, and superior to microarrays. We used the approach to map polyadenylation (polyA) si...
ORGANISM(S): Homo sapiens 
2011-06-25 | E-GEOD-30198 | biostudies-arrayexpress
UnknownPharmacogenomic discovery of genetically targeted cancer therapies optimized against clinical outcomes.
Not available
S-EPMC11358483 | biostudies-literature
TranscriptomicsSMAUG Is a Major Regulator of Maternal mRNA Destabilization in Drosophila
In animals, egg activation triggers a cascade of posttranscriptional events that act on maternally synthesized RNAs. We show that, in Drosophila, the PAN GU (PNG) kinase sits near the top of this cascade, triggering translation of SMAUG (SMG), a multifunctional posttranscriptional regulator conserve...
ORGANISM(S): Drosophila melanogaster 
2007-09-13 | E-GEOD-8910 | biostudies-arrayexpress
TranscriptomicsExpression of known and predicted genes in tissues of Gallus gallus (chicken)
Expression of known and predicted genes in tissues of Gallus gallus (chicken) pooled from multiple healthy individuals. Two-colour experiments with two different tissues hybridized to each array. Each tissue is arrayed in replicate with dye swaps. Tissues: Bursa of Fabricius, Cerebellum, Cerebral co...
ORGANISM(S): Gallus gallus 
2010-06-19 | E-GEOD-12974 | biostudies-arrayexpress
TranscriptomicsExpression of known and predicted genes in tissues of Xenopus tropicalis (frog)
Expression of known and predicted genes in tissues of Xenopus tropicalis (frog) pooled from multiple healthy individuals. Two-colour experiments with two different tissues hybridized to each array. Each tissue is arrayed in replicate with dye swaps. Tissues: Brain, Cartilage, Esophagus, Eye, Fat bod...
ORGANISM(S): Xenopus (Silurana) tropicalis 
2010-06-19 | E-GEOD-12975 | biostudies-arrayexpress
TranscriptomicsExpression of known and predicted genes in tissues of Tetraodon nigroviridis (pufferfish)
Expression of known and predicted genes in tissues of Tetraodon nigroviridis (pufferfish) pooled from multiple healthy individuals. Two-colour experiments with two different tissues hybridized to each array. Each tissue is arrayed in replicate with dye swaps. Tissues: Beak, Brain, Calvaria, Connecti...
ORGANISM(S): Tetraodon nigroviridis 
2010-06-19 | E-GEOD-12976 | biostudies-arrayexpress
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