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TranscriptomicsDifferential functional effects of EGF along the human fetal intestine
Transcriptional profiling of small and large intestinal explants cultured in the absence or in the presence of EGF (50 ng/mL). Two-condition experiment, control intestinal explants vs EGF intestinal explants
ORGANISM(S): Homo sapiens 
2012-01-11 | E-GEOD-18367 | biostudies-arrayexpress
TranscriptomicsAnti-Inflammatory Effects of Epidermal Growth Factor on the Immature Human Intestine
The inflammatory response of preterm infants' intestine underlines its inability to respond to hemodynamic stress, microbes and nutrients. Recent evidence suggests that exogenous epidermal growth factor (EGF) exerts a therapeutic influence on neonatal enteropathies. However, the molecular mechanism...
ORGANISM(S): Homo sapiens 
2012-01-11 | E-GEOD-33806 | biostudies-arrayexpress
TranscriptomicsGene expression profile analysis in the mid-gestation human intestine discloses greater immaturity of the colon as compared to ileum
The occurrence of many neonatal inflammatory intestinal diseases in preterm infants highlights the susceptibility of the immature intestine to respond inadequately to nutrient and microbes. A better understanding of the functional intestinal development is essential for the design of optimal treatme...
ORGANISM(S): Homo sapiens 
2011-01-01 | E-GEOD-20983 | biostudies-arrayexpress
TranscriptomicsDifferential functional effects of Indomethacin along the human fetal intestine
Transcriptional profiling of small and large intestinal explants cultured in the absence or in the presence of Indomethacin (1 µM). Two-condition experiment, control intestinal explants vs Indomethacin intestinal explants #4 replicates were normalized in a separate batch from the other replicates.
ORGANISM(S): Homo sapiens 
2013-01-01 | E-GEOD-38406 | biostudies-arrayexpress
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