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TranscriptomicsIdentification of a DNA methylation signature in blood from subjects affected by Down syndrome
Down syndrome is characterized by a wide spectrum of clinical signs, which include cognitive and endocrine disorders and haematological abnormalities. Although it is well established that the causative defect of Down syndrome is the trisomy of chromosome 21, the molecular bases of Down syndrome phen...
ORGANISM(S): Homo sapiens 
2015-03-03 | E-GEOD-52588 | biostudies-arrayexpress
TranscriptomicsDNA methylation profiles of brain samples from Down Syndrome subjects and controls.
Human DNA methylation Beadchip v1.2 was used to obtain DNA methylation profiles across approximately 486,000 CpGs. Dataset included 71 samples from multiple brain regions (cerebellum, temporal/occipital/frontal cortex). The goal was to evalute the effect of trisomy 21 on DNA methylation levels and e...
ORGANISM(S): Homo sapiens 
2015-03-02 | E-GEOD-63347 | biostudies-arrayexpress
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Not available
S-EPMC3258657 | biostudies-literature
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S-EPMC5522036 | biostudies-literature
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S-EPMC8130175 | biostudies-literature
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S-EPMC11818491 | biostudies-literature
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S-EPMC10577576 | biostudies-literature
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S-EPMC5355058 | biostudies-literature
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S-EPMC12000434 | biostudies-literature
UnknownReplicative Senescence-Associated LINE1 Methylation and LINE1-Alu Expression Levels in Human Endothelial Cells.
Not available
S-EPMC9739197 | biostudies-literature
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