Sort   by:  
 Page size 
ProteomicsIdentification of the Kinase phosphorylation sites on AtGPA1 in presence of GTP
Phosphorylation of GPA1 has been shown to functionally important in vitro and in vivo. We previously identified18 LRR RLKs transphosphorylation of AtGPA1 via in vitro kinase assay using recombinant kinase domains and AtGPA1 (Bo et al., J Biol Chem 293(13): 4752-4766). Among them, we choose 12 kinase...
ORGANISM(S): Arabidopsis Thaliana (ncbitaxon:3702) 
2019-06-12 | MSV000083964 | MassIVE
ProteomicsIdentification of the Kinase phosphorylation sites on AtGPA1 in presence of GDP
Phosphorylation of GPA1 has been shown to functionally important in vitro and in vivo. We previously identified18 LRR RLKs transphosphorylation of AtGPA1 via in vitro kinase assay using recombinant kinase domains and AtGPA1 (Bo et al., 2018, J. Biol. Chem 293(13): 4752-4766). Among them, we here cho...
ORGANISM(S): Arabidopsis Thaliana (ncbitaxon:3702) 
2019-06-12 | MSV000083963 | MassIVE
GenomicsInitiation of MLL-rearranged AML is orchestrated by C/EBPa
Acute Myeloid Leukemia (AML) is associated with a number of genetic and epigenetic events that result in malignant transformation of hematopoietic cells. In particular, transcription factors essential for normal hematopoiesis and stem cell function are often found mutated leading to the formation of...
ORGANISM(S): Mus musculus 
2013-12-10 | E-GEOD-47003 | biostudies-arrayexpress
TranscriptomicsDevelopment of MLL-rearranged leukemia is dependent on a transcriptional program orchestradt by C/EBPα
Translocations involving the MLL genes are frequently found in Acute Myeloid Leukemia (AML) and are associated with poor prognosis. The MLL fusion proteins act as aberrant transcription factor activating a transcriptional program that transforms the cells, potentially through collaboration with othe...
ORGANISM(S): Mus musculus 
2013-12-10 | E-GEOD-46534 | biostudies-arrayexpress
GenomicsExtra centrosomes delay DNA damage-driven tumorigenesis
Centrosomes act as microtubule organizing centers and are critical for faithful chromosome segregation in mitosis. Deregulated centrosome numbers are frequently found in human cancer and can promote malignancies in model organisms. Current research aims to clarify if extra centrosomes are cause or c...
ORGANISM(S): Mus musculus 
2026-01-22 | E-MTAB-13724 | biostudies-arrayexpress
TranscriptomicsGene Expression Profiling during Male Gametophyte Development in Rice
To investigate the potential function of miRNAs during male gametogenesis in rice, we first obtained gene expression profiles by using Affymetrix microarray technologies. In genome-scale, we found a common characteristic shared by rice and Arabidopsis, which vast of genes are down regulated from Pb ...
ORGANISM(S): Oryza sativa Indica Group 
2012-03-15 | E-GEOD-29080 | biostudies-arrayexpress
ProteomicsG1P promotes phase separation of glycogen and G6PD resulting in pentose phosphate pathway compartmentalization in CD8+ memory T cells
Glucose-6-phosphate (G6P) is a key metabolic molecule that regulates reactive oxygen species (ROS) homeostasis by initiating the pentose phosphate pathway (PPP) to generate NADPH that converts H2O2 to water by providing hydrogen. While both glucose phosphorylation and glycogenolysis result in G6P pr...
ORGANISM(S): Mus Musculus 
2025-05-07 | PXD063702 |
TranscriptomicsProfiling of small RNA populations in tricellular pollen of rice
To investigate the potential function of miRNAs during male gametogenesis in rice, 13-40 nt RNA were extrected from tricellular pollen (TCP) for high-throughput sequencing. We identified 104 unique miRNAs from TCP library, 57 of which are novel derived from 39 pre-miRNAs. This subseries contain one ...
ORGANISM(S): Oryza sativa Indica Group 
2012-03-15 | E-GEOD-29178 | biostudies-arrayexpress
GenomicsC/EBPa is required for self-renewal, lineage priming and maintenance of epigenetic configurations in hematopoietic stem cells
Transcription factors are key regulators of hematopoieticstem cells (HSCs) and act through their ability to bind DNA andimpact on gene transcription. Their functions are interpreted inthe complex landscape of chromatin but current knowledge on howthis is achieved is very limited. C/EBPa is an import...
ORGANISM(S): Mus musculus 
2013-12-01 | E-GEOD-43007 | biostudies-arrayexpress
UnknownFUTURE-AI: international consensus guideline for trustworthy and deployable artificial intelligence in healthcare.
Not available
S-EPMC11795397 | biostudies-literature
Sort   by:  
 Page size