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TranscriptomicsThe HDAC inhibitor LBH589 enhances the anti-myeloma effect of the IGF-1 RTK inhibitor picropodophyllin (PPP)
Our previous studies have shown that inhibition of the IGF-1R pathway by the IGF-1RTK inhibitor picropodophyllin (PPP) can be achieved and also constitutes a favorable therapeutic window in multiple myeloma (MM). As no complete remission using in vivo models of MM could be obtained, a combinatorial ...
ORGANISM(S): Homo sapiens 
2011-07-09 | E-GEOD-30524 | biostudies-arrayexpress
TranscriptomicsTCDD induced gene expression changes in dendritic cells
Effect of the over activation of the aryl hydrocarbon receptor on gene expression of spleen derived dendritic cells. 8-12 week old, female C57BL6 mice were injected 10 µg/kg TCDD i.p. or solvent control. After 24 h mice were sacrificed and splenic dendritic cells purified by MACS sorting.
ORGANISM(S): Mus musculus 
2008-11-25 | E-GEOD-13719 | biostudies-arrayexpress
UnknownImproving Care Pathways for Acute Coronary Syndrome: Patients Undergoing Percutaneous Coronary Intervention.
Not available
S-EPMC7809633 | biostudies-literature
TranscriptomicsTransforming growth factor-β and Notch ligands act as opposing environmental cues in the plasticity of type 3 innate lymphoid cells
Group 3 innate lymphoid cells (ILC3) are composed of NCR- and NCR+ subsets located at mucosal sites exposed to billions of commensal microbes and potentially harmful pathogens. Together with T cells, the various ILC3 subsets maintain the balance between homeostasis and immune activation. Using genet...
ORGANISM(S): Mus musculus 
2016-06-01 | E-GEOD-79410 | biostudies-arrayexpress
UnknownFeatures and Outcomes of 899 Patients With Drug-Induced Liver Injury: The DILIN Prospective Study.
Not available
S-EPMC4446235 | biostudies-literature
UnknownDevelopment and Validation of a Prediction Rule for Benefit and Harm of Dual Antiplatelet Therapy Beyond 1 Year After Percutaneous Coronary Intervention.
Not available
S-EPMC5408574 | biostudies-literature
UnknownHarmonization and standardization of nucleus pulposus cell extraction and culture methods.
Not available
S-EPMC10041384 | biostudies-literature
UnknownManagement of adult sepsis in resource-limited settings: global expert consensus statements using a Delphi method.
Not available
S-EPMC11787051 | biostudies-literature
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