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TranscriptomicsTranscritpome analysis of Mycobacterium tuberculosis (Mtb) mutants deficient in ergothioneine, or mycothiol production
This experiment was performed to determine deferentially regulated genes in the absence of redox buffer ergothioneine (EGT), or mycothiol (MSH). We had used two Mtb mutants namely egtA:Tn and egtD:Tn which are deficient in EGT production ( Transposon Mutant of EGT biosynthesis pathway); In additi...
ORGANISM(S): Mycobacterium tuberculosis CDC1551 
2016-01-27 | E-MTAB-4099 | biostudies-arrayexpress
TranscriptomicsTranscriptomic analysis of the estrogenic effect of soy protein isolate in rat uterus
There are concerns regarding possible reproductive toxicity from consumption of soy including an increased risk of endometriosis and endometrial cancer. We used global uterine gene expression profiles in adult ovariectomized (OVX) female rats assessed by RNAseq to examine the estrogenicity of soy pr...
ORGANISM(S): Rattus norvegicus 
2015-06-13 | E-GEOD-69819 | biostudies-arrayexpress
TranscriptomicsGenotyping of human glioma - assessing the significance of chromosomal aberrations in cancer
Comprehensive knowledge of the genomic alterations that underlie cancer is a critical foundation for diagnostics, prognostics and targeted therapeutics. Systematic efforts to analyze cancer genomes are underway, but the analysis is hampered by the lack of a statistical framework to distinguish mean...
ORGANISM(S): Homo sapiens 
2008-06-17 | E-GEOD-9635 | biostudies-arrayexpress
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