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The cohort comprised patients recruited between August 2014 - April 2017. It includes patients with bacteremia, positive viral diagnostic test in the context of acute admission and those with no positive microbial diagnostic test, no infection-related ICD-10 diagnostic codes, and no empirical antivi...
ORGANISM(S): Homo sapiens 
Streptococcus pneumoniae is a common nasopharyngeal colonizer, but can also cause life-threatening invasive diseases such as empyema, bacteremia and meningitis. Genetic variation of host and pathogen is known to play a role in invasive pneumococcal disease, though to what extent is unknown. This st...
Targeted genomic enrichment followed by next-generation sequencing dramatically increased the efficiency of mutation discovery in human genomes. Here we demonstrate that these techniques also revolutionize traditional genetic approaches in model systems. We developed a two-step protocol utilizing a ...
ORGANISM(S): Rattus norvegicus 
Pseudomonas aeruginosa can adhere to and be internalized by airway epithelial cells, but the host and bacterial responses during bacterial adhesion and intracellular infection remain incompletely understood. In this study, we characterized the proteomes of P. aeruginosa PAO1 and CuFi-5 human airway ...
ORGANISM(S): Homo sapiens (Human) Pseudomonas aeruginosa 
2026-08-07 | PXD081656 | Pride
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