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H3K36 methylation by Set2 targets Rpd3S histone deacetylase to 3’ transcribed regions, repressing internal cryptic promoters and slowing elongation. To further explore the function of this pathway, global transcription was analyzed in yeast experiencing a series of carbon source shifts. Many pr...
ORGANISM(S): Saccharomyces cerevisiae 
The objective of this study was to evaluate the efficacy of nicotinamide in a N-butyl-N-(4-hydroxybutyl)-nitrosamine (BBN)-induced urinary bladder cancer model in mice, and to identify through gene expression profiling the molecular signatures of cancer prevention by nicotinamide. We used 20 mice fo...
ORGANISM(S): Mus musculus 
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