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TranscriptomicsTarget-gene mediated activation of phosphatase activity of sensor kinase in the SaeRS two-component system of Staphylococcus aureus
In bacterial two-component regulatory systems (TCSs), dephosphorylation of phosphorylated response regulator is essential for resetting the activated systems to the pre-activation state. However, in the SaeRS TCS, a major virulence TCS of Staphylococcus aureus, the mechanism for dephosphorylation of...
ORGANISM(S): Staphylococcus aureus subsp. aureus USA300 
2012-03-09 | E-GEOD-36230 | biostudies-arrayexpress
TranscriptomicsTranscriptome analysis of Newman delta2027
Intracellular small-molecule signaling has drawn increasing attention due to its importance in bacterial physiology and host-pathogen interactions. Here, we show that a new quinone-sensing transcriptional regulator, QsbR (quinone-stress sensing and bleomycin resistance regulator), is important for b...
ORGANISM(S): Staphylococcus aureus subsp. aureus str. Newman 
2012-03-09 | E-GEOD-35409 | biostudies-arrayexpress
TranscriptomicsRole of the prophages in the Staphylococcus aureus pathogenesis
Staphylococcus aureus is a Gram-positive human pathogen causing a variety of human diseases in both hospital and community settings. This bacterium is so closely associated with prophages that it is rare to find S. aureus isolates without prophages. Two phages are known to be important for staphyloc...
ORGANISM(S): Staphylococcus aureus 
2011-02-28 | E-GEOD-26623 | biostudies-arrayexpress
TranscriptomicsRole of the yhcR in the Staphylococcus aureus gene expression
Staphylococcus aureus is a Gram-positive human pathogen causing a variety of human diseases in both hospital and community settings. This bacterium is so closely associated with prophages that it is rare to find S. aureus isolates without prophages. Two phages are known to be important for staphyloc...
ORGANISM(S): Staphylococcus aureus subsp. aureus str. Newman 
2011-12-31 | E-GEOD-26585 | biostudies-arrayexpress
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