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Nonalcoholic steatohepatitis (NASH) prevalence is rising with no pharmacotherapy approved. A major hurdle in NASH drug development is the poor translatability of preclinical studies to safe/effective clinical outcomes, and recent failures highlight a need to identify new targetable pathways. Dysr...

2023-04-13 | MTBLS5005 | MetaboLights
We used interaction and expression proteomic techniques in conjunction with RNA-Seq transcriptomic analysis to analyse how a β-catenin stabilizing mutation alters molecular networks in colorectal cancer cells. Integrated computational analyses of allowed us to identify significantly altered sub-netw...
ORGANISM(S): Homo sapiens (Human) 
2018-05-18 | PXD006053 | Pride
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