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TranscriptomicsComparison of gene regulation by Gcn5 under KCl stress in S. cerevisiae and S. pombe
This is parallel comparison of gene regulation by Gcn5 in evolutionarily divergent yeasts S. pombe and S. cerevisiae. Our study showed Gcn5 is required for a similar spectrum of stress responses in both organisms, including the response to KCl. This DNA microarray studies is to find conserved or div...
ORGANISM(S): Saccharomyces cerevisiae 
2010-06-24 | E-GEOD-5218 | biostudies-arrayexpress
MetabolomicsMetabolic phenotyping of urine from a dementia research cohort
To better understand the molecular mechanisms underpinning physiological variation in human populations, metabolic phenotyping approaches are increasingly being applied to studies involving hundreds and thousands of biofluid samples. Hyphenated ultra-performance liquid chromatography-mass spectromet...
2022-03-01 | MTBLS719 | MetaboLights
TranscriptomicsMutant2
Cells in glucose-limited Saccharomyces cerevisiae cultures differentiate into quiescent (Q) and non-quiescent (NQ) fractions prior to entering stationary phase. To identify genes involved in this differentiation, Q and NQ cells from 101 deletion-mutant strains were tested for viability and reproduc...
ORGANISM(S): Saccharomyces cerevisiae 
2007-12-26 | E-GEOD-8561 | biostudies-arrayexpress
TranscriptomicsMutant1
Cells in glucose-limited Saccharomyces cerevisiae cultures differentiate into quiescent (Q) and non-quiescent (NQ) fractions prior to entering stationary phase. To identify genes involved in this differentiation, Q and NQ cells from 101 deletion-mutant strains were tested for viability and reproduc...
ORGANISM(S): Saccharomyces cerevisiae 
2007-12-26 | E-GEOD-8560 | biostudies-arrayexpress
TranscriptomicsS288c Quiescent and Non-quiescent replicates
Cells in glucose-limited Saccharomyces cerevisiae cultures differentiate into quiescent (Q) and non-quiescent (NQ) fractions prior to entering stationary phase. To identify genes involved in this differentiation, Q and NQ cells from 101 deletion-mutant strains were tested for viability and reproduc...
ORGANISM(S): Saccharomyces cerevisiae 
2010-05-27 | E-GEOD-8559 | biostudies-arrayexpress
TranscriptomicsBY4742 Quiescent and Non-quiescent replicates
Cells in glucose-limited Saccharomyces cerevisiae cultures differentiate into quiescent (Q) and non-quiescent (NQ) fractions prior to entering stationary phase. To identify genes involved in this differentiation, Q and NQ cells from 101 deletion-mutant strains were tested for viability and reproduc...
ORGANISM(S): Saccharomyces cerevisiae 
2010-05-27 | E-GEOD-8542 | biostudies-arrayexpress
TranscriptomicsProteinase K treatment of Q and NQ cells
Cells in glucose-limited Saccharomyces cerevisiae cultures differentiate into quiescent (Q) and non-quiescent (NQ) fractions prior to entering stationary phase. To identify genes involved in this differentiation, Q and NQ cells from 101 deletion-mutant strains were tested for viability and reproduc...
ORGANISM(S): Saccharomyces cerevisiae 
2010-05-27 | E-GEOD-8558 | biostudies-arrayexpress
TranscriptomicsIntegrated nuclear proteomics and transcriptomics identifies new high frequency dysregulated targets in acute myeloid leukemia
Acute myeloid leukemia (AML) is characterized by developmental arrest which is thought to arise from transcriptional dysregulation of myeloid development programs. Here, we have analyzed the transcriptome of AML blasts in comparison with normal human CD34+ cells using the HTA 2.0 gene chip. We have ...
ORGANISM(S): Homo sapiens 
2019-10-02 | E-MTAB-3873 | biostudies-arrayexpress
TranscriptomicsDivergence of Transcription Factor Binding Sites in Related Yeast Species
A fundamental problem in biology is the molecular basis for divergence among related organisms. We have investigated the level of divergence of transcription factor binding sites for two key factors that regulate developmental processes in the budding yeasts. The genomic binding locations for the St...
ORGANISM(S): Saccharomyces mikatae 
2007-09-06 | E-GEOD-5421 | biostudies-arrayexpress
UnknownOperative vs Nonoperative Treatment of Acute Unstable Chest Wall Injuries: A Randomized Clinical Trial.
Not available
S-EPMC9494266 | biostudies-literature
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