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TranscriptomicsEnhancer chromatin signatures predict Smad2/3 binding in Xenopus
In this study we have examine the deposition of H3K4me1,H3K4Me3 and H3K27Ac and the Nodal transcription factor, Smad2/3, immediately following zygotic transcription and continuing through gastrulation. We profiled 4 histone modifications (H3K4Me3, H3K27Me3, H3K27AC, H3K4Me1) and one transcription fa...
ORGANISM(S): Xenopus (Silurana) tropicalis 
2014-09-17 | E-GEOD-56000 | biostudies-arrayexpress
TranscriptomicsConstraint and divergence of global gene expression in the mammalian embryo
We profiled genome-wide gene expression of 170 individual mid-gestation (embryonic day 11.5) whole mouse embryos derived from a 2-generation interspecies mouse cross and asked to what extent genetic variation drives four important parameters of regulatory architecture: allele-specific expression (AS...
ORGANISM(S): Mus musculus 
2015-04-14 | E-GEOD-62967 | biostudies-arrayexpress
TranscriptomicsTranscriptional Control by the FATC Domain of Saccharomyces cerevisiae Tra1
Tra1 is a component of the Saccharomyces cerevisiae SAGA and NuA4 complexes and a member of the phosphatidylinositol 3-kinase (PI3K) related kinase family that contain a C- terminal PI3K domain followed by a ~ 35-residue FATC domain. We have characterized four alleles with single residue changes in ...
ORGANISM(S): Saccharomyces cerevisiae 
2013-01-30 | E-GEOD-13561 | biostudies-arrayexpress
UnknownSystemic Therapy for Stage IV Non-Small-Cell Lung Cancer: American Society of Clinical Oncology Clinical Practice Guideline Update.
Not available
S-EPMC5019421 | biostudies-literature
TranscriptomicsRole of Histone Ubiquitylation and Deubiquitylation as Determined by the Analysis of an HTB1_K123R S. cerevisiae Strain
In Saccharomyces cerevisiae histone H2B is ubiquitylated at lysine 123. The SAGA complex component, Ubp8, is one of two proteases that remove this ubiquitin moiety. We analyzed gene expression in a strain containing a variant of histone H2B with lysine 123 converted to arginine to address the mechan...
ORGANISM(S): Saccharomyces cerevisiae 
2010-09-15 | E-GEOD-6316 | biostudies-arrayexpress
TranscriptomicsMicrofluidic platform for monitoring Saccharomyces cerevisiae mutation accumulation assay
Saccharomyces cerevisiae wildtype (YPH) and ung1-deleted strains were cultivated in mutation accumulation experiments over several bottlenecks (0-50-100-150). Two different cutlure systems were used either (i) using random colony selection and plating on petri dish (classical); or (ii) a microfluidi...
ORGANISM(S): Saccharomyces cerevisiae S288C 
2021-08-01 | E-MTAB-10259 | biostudies-arrayexpress
TranscriptomicsGene profiling of TRA1 and tra1-L3733A
Tra1 is a component of the Saccharomyces cerevisiae SAGA and NuA4 complexes and a member of the phosphatidylinositol 3-kinase kinase family that contain a C-terminal PI3K domain followed by a 35-residue FATC domain. We analyzed alleles with single residue changes in the FATC domain. Of these tra1-L3...
ORGANISM(S): Saccharomyces cerevisiae 
2010-09-19 | E-GEOD-18591 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of Xenopus laevis gastrula ventral and dorsal halves at NF stages 10 and 11.5 injected with noggin and dkk-1 plasmid
Studies of the Xenopus organizer have laid the foundation for our understanding of the conserved signaling pathways that pattern vertebrate embryos during gastrulation. Here, we use this wealth of knowledge as leverage in the design and analysis of a genomic visualization of organizer-related gene ...
ORGANISM(S): Xenopus laevis 
2007-10-05 | E-GEOD-3368 | biostudies-arrayexpress
Unknown2011 Focused Update of 2009 American Society of Clinical Oncology Clinical Practice Guideline Update on Chemotherapy for Stage IV Non-Small-Cell Lung Cancer.
Not available
S-EPMC3675703 | biostudies-literature
TranscriptomicsGenome-wide occupancy of Bye1, TFIIS and Pol II in yeast Saccharomyces cerevisiae by ChIP-chip
The aim of this experiment is to assess the genome-wide occupancy of Bye1, TFIIS and RNA polymerase II in yeast Saccharomyces cerevisiae by ChIP-chip
ORGANISM(S): Saccharomyces cerevisiae 
2014-12-05 | E-MTAB-2161 | biostudies-arrayexpress
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