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TranscriptomicsTranscription profiling of Drosophila developmental time series
Michelle N. Arbeitman, Eileen E. M. Furlong, Farhad Imam, Eric Johnson, Brian H. Null, Bruce S. Baker, Mark A. Krasnow, Matthew P. Scott, Ronald W. Davis and Kevin P. White. Gene Expression During the Life Cycle of Drosophila melanogaster, Science, 297: 2270-2275, 2002. This work can be accessed fro...
ORGANISM(S): Drosophila melanogaster 
2004-11-06 | E-FLYC-6 | biostudies-arrayexpress
TranscriptomicsYeast m6A methylated mRNAs are enriched on translating ribosomes during meiosis, and under Rapamycin treatment
Interest in mRNA methylation has exploded in recent years. The sudden interest in a 40 year old discovery was due in part to the recent finding of FTO?s (Fat Mass Obesity) N6-methyl-adenosine (m6A) deaminase activity, thus suggested a link between obesity-associated diseases and the presence of m6A...
ORGANISM(S): Saccharomyces cerevisiae SK1 
2015-08-12 | E-GEOD-68435 | biostudies-arrayexpress
TranscriptomicsR-loops are marks for histone H3 Ser10 phosphorylation and chromatin compaction
R-loops are transcription by-products that may constitute a threat to genome integrity. In addition to specific enzymes to remove them, eukaryotes rely on a number of mRNP biogenesis factors such as the THO complex, to prevent co-transcriptional R-loop formation. We show in Saccharomyces cerevisiae ...
ORGANISM(S): Saccharomyces cerevisiae 
2013-11-13 | E-GEOD-46627 | biostudies-arrayexpress
TranscriptomicsChromatin immunoprecipitation of wild type, SET2 deletion, Rco1 PHD domain deletion and Eaf3 chromodomain deletion yeast using anti-acetyl-histone H4
Nucleosomes must be deacetylated behind elongating RNA polymerase II to prevent cryptic initiation of transcription within the coding region. RNA polymerase II signals for deacetylation through methylation of histone H3 lysine 36 (H3K36) which provides the recruitment signal for the Rpd3S deacetylas...
ORGANISM(S): Saccharomyces cerevisiae 
2007-05-16 | E-TABM-260 | biostudies-arrayexpress
UnknownScm3, an essential Saccharomyces cerevisiae centromere protein required for G2/M progression and Cse4 localization.
Not available
S-EPMC1885823 | biostudies-literature
UnknownInitial clinical experience with the balloon-in-basket pulsed field ablation system: acute results of the VOLT CE mark feasibility study.
Not available
S-EPMC11098042 | biostudies-literature
GenomicsGlutamine methylation on Histone H2A is an RNA Polymerase I dedicated modification
Nucleosomes are decorated with numerous post-translational modifications capable of influencing many DNA processes. Here, we describe a new class of modification, methylation of glutamine, occurring on yeast histone H2A at position 105 (Q105) and human H2A at Q104. We identify Nop1 as the methyltran...
ORGANISM(S): Saccharomyces cerevisiae 
2014-01-21 | E-MTAB-1447 | biostudies-arrayexpress
UnknownPhase IB Study of Selinexor, a First-in-Class Inhibitor of Nuclear Export, in Patients With Advanced Refractory Bone or Soft Tissue Sarcoma.
Not available
S-EPMC5321073 | biostudies-literature
GenomicsTargets of Ty3 transposition in Saccharomyces cerevisiae
The goal of these experiments was to define the targets of Ty3 transposition in Saccharomyces cerevisiae. Ty3 is a retroviruslike element that is found at the transcription initiation site of chromosomal tRNA genes. A Ty3 that can be induced by growth in galactose-containing medium and which was ma...
ORGANISM(S): Saccharomyces cerevisiae 
2011-09-02 | E-GEOD-31820 | biostudies-arrayexpress
ProteomicsThe role of HnrnpF/H as a driver of Oligoteratozoospermia
Male subfertility or infertility is a common condition often characterized by men producing a low number of sperm with poor quality. To gain insight into this condition, we performed a quantitative proteomic analysis of semen samples obtained from infertile and fertile men.
ORGANISM(S): Homo sapiens (Human) 
2024-08-09 | PXD046594 | Pride
Human Sperm Male infertility Swath-ms 
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