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TranscriptomicsSomatic cell nuclear reprogramming by mouse oocytes endures beyond reproductive decline
The mammalian oocyte has the unique feature of supporting fertilization and normal development while being able of reprogramming the nuclei of somatic cells towards pluripotency and occasionally even totipotency. Whilst oocyte quality is known to decay with somatic aging it is not a given that diffe...
ORGANISM(S): Mus musculus 
2011-08-15 | E-GEOD-23654 | biostudies-arrayexpress
TranscriptomicsReprogramming of two somatic nuclei in the same ooplasm leads to pluripotent embryonic stem cells
We provide proof that the oocyte is able to reprogram two somatic nuclei at once and therefore is not limited in its reprogramming capacity to a single nucleus. Mouse ooplasts transplanted with 2 somatic cell nuclei simultaneously (double nuclear transfer) support preimplantation development and the...
ORGANISM(S): Mus musculus 
2013-07-11 | E-GEOD-36468 | biostudies-arrayexpress
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