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UnknownHuman endogenous retrovirus-K (HERV-K) reverse transcriptase (RT) structure and biochemistry reveals remarkable similarities to HIV-1 RT and opportunities for HERV-K-specific inhibition.
Not available
S-EPMC9271190 | biostudies-literature
UnknownEnzymatic catalysis of anti-Baldwin ring closure in polyether biosynthesis.
Not available
S-EPMC3401210 | biostudies-literature
MetabolomicsNavigating natural variation in herbivory-induced secondary metabolism in coyote tobacco populations using MS/MS structural analysis
Natural variation can be extremely useful in unraveling the determinants of phenotypic trait evolution but has rarely been analyzed with unbiased metabolic profiling to understand how its effects are organized at the level of biochemical pathways. Native populations of Nicotiana attenuata, a wild to...
2015-06-15 | MTBLS203 | MetaboLights
UnknownA rare mutation in ABCC8/SUR1 leading to altered ATP-sensitive K+ channel activity and beta-cell glucose sensing is associated with type 2 diabetes in adults.
Not available
S-EPMC6101196 | biostudies-literature
TranscriptomicsTranscriptional Profiling is Superior to Procalcitonin to Discriminate Bacterial vs. Viral Lower Respiratory Tract Infections in Hospitalized Adults
Background: Distinguishing between bacterial and viral lower respiratory tract infections (LRTI) in hospitalized patients remains challenging. Transcriptional profiling is a promising tool for improving diagnosis in LRTI. Methods: We performed whole blood transcriptional analysis in a cohort of ...
ORGANISM(S): Homo sapiens 
2015-09-14 | E-GEOD-60244 | biostudies-arrayexpress
MetabolomicsThe downside of metabolic diversity: Postingestive rearrangements by specialized insects
Deploying toxins in complex mixtures is thought to be advantageous and is observed during antagonistic interactions in nature. Toxin mixtures are widely utilized in medicine and pest control, as they are thought to slow the evolution of detoxification counterresponses in the targeted organisms. Here...
2022-12-04 | MTBLS3676 | MetaboLights
UnknownLong-term protective efficacy with a BCG-prime ID93/GLA-SE boost regimen against the hyper-virulent Mycobacterium tuberculosis strain K in a mouse model.
Not available
S-EPMC6820558 | biostudies-literature
UnknownNucleobase transport by human equilibrative nucleoside transporter 1 (hENT1).
Not available
S-EPMC3173155 | biostudies-literature
MetabolomicsSpecific decorations of 17-hydroxygeranyllinalool diterpene glycosides solve the autotoxicity problem of chemical defense in Nicotiana attenuata
The native diploid tobacco Nicotiana attenuata produces abundant, potent anti-herbivore defense metabolites known as 17-hydroxygeranyllinalool diterpene glycosides (HGL-DTGs) whose glycosylation and malonylation biosynthetic steps are regulated by jasmonate signaling. To characterize the biosyntheti...
2021-10-06 | MTBLS1819 | MetaboLights
UnknownK<sub>V</sub>7 Channel Expression and Function Within Rat Mesenteric Endothelial Cells.
Not available
S-EPMC7750541 | biostudies-literature
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